PHENETHYL ALCOHOL
PHENETHYL ALCOHOL
Phenethyl alcohol is an organic compound with the chemical formula C6H5CH2CH2OH.
Phenethyl alcohol is a colourless liquid with a pleasant floral odor.
Phenethyl alcohol occurs widely in nature, being found in a variety of essential oils.
CAS Number: 60-12-8
EC Number: 200-456-2
Molecular Formula: C8H10O
Molecular Weight: 122.16
Synonyms: 2-PHENYLETHANOL, Phenethyl alcohol, Phenylethyl alcohol, 60-12-8, Benzeneethanol, Phenylethanol, Benzyl carbinol, Phenethanol, 2-Phenylethyl alcohol, 2-PHENYL-ETHANOL, beta-Phenylethanol, 2-Phenethyl alcohol, Benzylmethanol, 2-Phenylethan-1-Ol, Benzylcarbinol, Methanol, benzyl-, 2-Hydroxyethylbenzene, 1-Phenyl-2-ethanol, Ethanol, 2-phenyl-, FEMA No. 2858, 2-PEA, Benzenethanol, Phenethylalcohol, Phenyl ethyl alcohol, beta-PEA, beta-Phenylethyl alcohol, beta-Hydroxyethylbenzene, Caswell No. 655C, beta-Fenylethanol, FEMA Number 2858, 1321-27-3, beta-Fenethylalkohol, Phenethyl alcohol (natural), beta-Phenethyl alcohol, HSDB 5002, 2-Phenethanol, .beta.-Hydroxyethylbenzene, .beta.-Phenylethyl alcohol, Hydroxyethylbenzene, EINECS 200-456-2, UNII-ML9LGA7468, MFCD00002886, PhenethylAlcohol-d5, EPA Pesticide Chemical Code 001503, NSC 406252, NSC-406252, BRN 1905732, .beta.-Phenylethanol, ML9LGA7468, .beta.-PEA, DTXSID9026342, CHEBI:49000, AI3-00744, (2-Hydroxyethyl)benzene, .beta.-Phenethyl alcohol, Phenylethyl alcohol [USP], .beta.-(hydroxyethyl)benzene, DTXCID206342, EC 200-456-2, 4-06-00-03067 (Beilstein Handbook Reference), NSC406252, NCGC00166215-02, Phenylethyl alcohol (USP), Ethanol, phenyl-, PHENYLETHYL ALCOHOL (II), PHENYLETHYL ALCOHOL [II], PHENETHYL ALCOHOL (MART.), PHENETHYL ALCOHOL [MART.], Phenyl Ethanol(Natural), 2 Phenylethanol, PHENYLETHYL ALCOHOL (USP-RS), PHENYLETHYL ALCOHOL [USP-RS], beta-Fenylethanol [Czech], 2-phenyl ethanol, Carbinol, Benzyl, beta Phenylethanol, CAS-60-12-8, Alcohol, Phenethyl, beta-Fenethylalkohol [Czech], PEL, SMR000059156, PHENYLETHYL ALCOHOL (USP MONOGRAPH), PHENYLETHYL ALCOHOL [USP MONOGRAPH], Alcohol, Phenylethyl, benzene-ethanol, Mellol, phenyl-ethanol, Benzyl-Methanol, 2-PhenyIethanol, phenylethyl-alcohol, .beta.-Phenethanol, HY1, .beta.-Fenylethanol, b-Hydroxyethylbenzene, Benzyl ethyl alcohol, 2-phenyl-1-ethanol, Benzeneethanol, 9CI, 2-phenylethane-1-ol, betaphenylethyl alcohol, .beta.-Fenethylalkohol, 2-Phenylethanol, USP, METHANOL, BENZYL, A-PEA, beta -hydroxyethylbenzene, 2-Phenylethanol, 99%, .beta.-P.E.A., (BETA-PEA), Phenylethyl alcohol, USAN, bmse000659, Phenylethyl, beta- alcohol, 2-(2-Hydroxyethyl)benzene, SCHEMBL1838, WLN: Q2R, MLS001066349, MLS001336026, FEMA NUMBER 2858., PHENETHYL ALCOHOL [MI], Phenethyl alcohol, 8CI, BAN, CHEMBL448500, beta-(HYDROXYETHYL)BENZENE, PHENETHYL ALCOHOL [FCC], PHENYLETHYL, B- ALCOHOL, PHENETHYL ALCOHOL [INCI], BDBM85807, FEMA 2858, HMS2093H05, HMS2233H06, HMS3374P04, Pharmakon1600-01505398, PHENYLETHYL ALCOHOL [FHFI], PHENYLETHYL ALCOHOL [HSDB], PHENETHYL ALCOHOL [WHO-DD], BCP32115, CS-B1821, HY-B1290, NSC_6054, Tox21_113544, Tox21_201322, Tox21_303383, NSC759116, s3703, 2-Phenylethanol, >=99.0% (GC), AKOS000249688, Tox21_113544_1, CCG-213419, DB02192, NSC-759116, CAS_60-12-8, Phenethyl alcohol, >=99%, FCC, FG, NCGC00166215-01, NCGC00166215-03, NCGC00166215-05, NCGC00257347-01, NCGC00258874-01, AC-18484, SBI-0206858.P001, FT-0613332, FT-0673679, P0084, EN300-19347, C05853, D00192, D70868, Phenethyl alcohol, natural, >=99%, FCC, FG, AB00698274_05, A832606, Q209463, SR-01000763553, Phenylethyl alcohol, >=99%, FCC, FG, Phenylethyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material, 19601-20-8.
Phenethyl alcohol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of phenethyl alcohol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
Phenethyl alcohol is an aromatic alcohol used as a flavoring agent in the cosmetic, perfume, and food industries.
Phenethyl alcohol, also known as 2-phenylethanol or beta-phenylethyl alcohol, is a colorless liquid with a floral, rose-like scent.
Phenethyl alcohol is a primary alcohol and belongs to the class of compounds known as phenols.
The chemical formula for phenethyl alcohol is C8H10O.
Phenethyl alcohol is a kind of edible spices, and naturally exists in neroli, rose oil, geranium oil and other oils, because Phenethyl alcohol has a soft, pleasant and persistent rose fragrance and is widely used in various kinds of flavors and cigarette flavor.
Phenethyl alcohol is dispensing rose scent, food additives, the main raw material for rose scent flavor, stable on alkali, which are widely used in soap fragrance, is essence blending all rose scent series of spices, because Phenethyl alcohol does not dissolve in water, it is often used in the making up water, soap and orange flower, purple, etc.
Phenethyl alcohol is also used in the blending of flavor.
Because the Phenethyl alcohol has a good antibacterial efficiency, Phenethyl alcohol can be used in the ophthalmic solution.
Phenethyl alcohol has a characteristic rose-like odor and an initially slightly bitter taste, then sweet and reminiscent of peach.
Phenethyl alcohol, an aromatic alcohol with rose-like odor, is commonly used as a food flavoring and fragrance ingredient.
Phenethyl alcohol is the main flavor volatile of tomato and blue cheese.
Phenethyl alcohol is a clear, colorless liquid with an odor of rose oil.
Phenethyl alcohol has a burning taste that irritates and then anesthetizes mucous membranes.
Phenethyl alcohol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.
Phenethyl alcohol is active at pH 6 or less and is inactivated by nonionic detergents including polysorbate-80.
Phenethyl alcohol is also a widely used fragrance material that imparts a rose character to perfume compositions.
Almost all rose fragrances and other floral-type perfumes contain Phenethyl alcohol, and Phenethyl alcohol is used extensively for many other fragrance applications because Phenethyl alcohol blends ell.
Phenethyl alcohol is metabolized to phenylacetic acid in mammals.
In humans, Phenethyl alcohol is excreted in urine as the conjugate phenylacetylglutamine.
Phenethyl Alcohol is a clear, colorless liquid with a floral fragrance that is commonly used in cosmetics and personal care products as a preservative.
Phenethyl alcohol is chemical formula is C8H10O, and Phenethyl alcohol is naturally derived from plants such as rose and jasmine.
Phenethyl Alcohol is effective against bacteria, fungi, and viruses, making Phenethyl alcohol a popular alternative to synthetic preservatives.
Phenethyl alcohol is soluble in both oil and water, which allows Phenethyl alcohol to be easily incorporated into a wide range of cosmetic formulations.
With Phenethyl alcohol natural origin and broad-spectrum antimicrobial properties, Phenethyl alcohol is a good choice for those looking for safe and effective preservatives.
2-phenylethanol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.
Phenethyl alcohol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.
Phenethyl alcohol is a primary alcohol and a member of benzenes.
Phenethyl alcohol, is a primary aromatic alcohol of high boiling point, having a characteristic rose-like odor.
Phenethyl alcohol presents organoleptic properties and impacts the quality of the wine, distilled beverages, and fermented foods.
Phenethyl alcohol shows its presence in fresh beer and is responsible for the rose-like odor of well-ripened cheese.
Phenethyl alcohol is commercially and industrially an important flavor and is a component of a variety of foodstuffs such as ice cream, gelatin, candy, pudding, chewing gum, and non-alcoholic beverages.
Phenethyl alcohol is formed by yeasts during fermentation of alcohols either by decomposition of L-phenylalanine or metabolism of sugar substrates.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Phenethyl alcohol is prepared commercially via two routes.
Most common is the Friedel-Crafts reaction between benzene and ethylene oxide in the presence of aluminium trichloride.
C6H6 + CH2CH2O + AlCl3 → C6H5CH2CH2OAlCl2 + HCl
The reaction affords the aluminium alkoxide that is subsequently hydrolyzed to the desired product.
The main side product is Phenethyl alcohol, which can be avoided by use of excess benzene.
Phenethyl alcohol of styrene oxide also affords phenethyl alcohol.
Phenethyl alcohol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Phenethyl alcohol is also an autoantibiotic produced by the fungus Candida albicans.
Phenethyl alcohol is therefore a common ingredient in flavors and perfumery, particularly when the odor of rose is desired.
Phenethyl alcohol is used as an additive in cigarettes.
Phenethyl alcohol is also used as a preservative in soaps due to Phenethyl alcohol stability in basic conditions.
Phenethyl alcohol is of interest due to its antimicrobial properties.
Phenethyl alcohol a colorless liquid used in small amounts as a so-called masking ingredient, meaning Phenethyl alcohol can hide the natural not-so-nice smell of other cosmetic ingredients.
Phenethyl alcohol has a nice rose-like scent and can be found in several essential oils such as rose, neroli or geranium.
Phenethyl alcohol also has some antimicrobial activity and can boost the performance of traditional preservatives.
Phenethyl alcohol is an aromatic alcohol that is used as a fragrance and an antimicrobial preservative in cosmetic formulations.
Phenethyl alcohol is an aromatic chemical, usually appearing as a clear oily liquid with a sweet rose scent.
Phenethyl alcohol can be synthesized for industry through the use of yeast strains or by reacting benzene and ethylene oxide with a catalyst.
Phenethyl alcohol is naturally present in grapes and wines, and is also found in the essential oils of many plants such as ylang ylang, hyacinth and carnation.
Phenethyl alcohol is the dominant odour in fresh roses such as Rosa multiflora, however is mostly lost during essential oil production as Phenethyl alcohol separates, with only a fraction remaining in rose oil.
Phenethyl alcohols are a large class of important cosmetic ingredients but only ethanol needs to be denatured to prevent Phenethyl alcohol from being redirected from cosmetic applications to alcoholic beverages.
Phenethyl alcohol is a colorless, transparent, slightly viscous liquid.
In cosmetics and personal care products, Phenethyl Alcohol is used in the formulation of eye area makeup, makeup products, skin care products, shampoos and perfumes and colognes.
Phenethyl alcohol is a primary alcohol that is ethanol substituted by a phenyl group at position 2.
Phenethyl alcohol has a role as a fragrance, a Saccharomyces cerevisiae metabolite, a plant metabolite, an Aspergillus metabolite and a plant growth retardant.
Phenethyl alcohol is a primary alcohol and a member of benzenes.
Phenethyl alcohol is a water soluble fragrance agent with rose like scent and good antimicrobial activity.
Perfect suitable for water based products and colour cosmetics.
The combination with boosting agents is in emulsions recommendable, the performance is pH independent.
Phenethyl alcohol, or 2-phenylethanol, is an organic compound with the chemical formula C6H5CH2CH2OH.
Phenethyl alcohol is a colourless liquid with a pleasant floral odor.
Phenethyl alcohol occurs widely in nature, being found in a variety of essential oils.
Phenethyl alcohol is slightly soluble in water (2 ml per 100 ml of H2O), but miscible with most organic solvents.
The molecule of phenethyl alcohol consists of a phenethyl group (C6H5CH2CH2−) attached to a hydroxyl group (−OH).
Phenethyl alcohol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid that is slightly soluble in water.
Phenethyl alcohol has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans.
Phenethyl alcohol is used as an additive in cigarettes and also used as a preservative in soaps due to Phenethyl alcohol stability in basic conditions.
Phenethyl alcohol is the deuterium labeled 2-Phenylethanol.
Phenethyl alcohol, extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid.
Phenethyl alcohol has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans.
Phenethyl alcohol is used as an additive in cigarettes and also used as a preservative in soaps due to Phenethyl alcohol stability in basic conditions.
Phenethyl alcohol occurs naturally in some essential oils, such as rose oil, carnation oil, and geranium oil, contributing to their pleasant fragrance.
Phenethyl alcohol is commonly used in the perfume and flavor industries due to Phenethyl alcohol floral aroma.
Additionally, phenethyl alcohol has antimicrobial properties, which makes Phenethyl alcohol useful in various cosmetic and personal care products as a preservative.
Phenethyl alcohol occurs naturally in various plants, including roses, carnations, geraniums, and other flowers.
Phenethyl alcohol is extracted from these sources for use in the fragrance industry.
One of the primary uses of phenethyl alcohol is in the fragrance and perfume industry.
Phenethyl alcohol is pleasant, floral scent, reminiscent of roses, makes Phenethyl alcohol a popular choice for adding a sweet and rosy note to perfumes and cosmetic products.
In addition to its use in perfumery, phenethyl alcohol is sometimes used as a flavoring agent in the food industry, providing a sweet and floral taste to certain products.
Phenethyl alcohol has antimicrobial properties, and as such, Phenethyl alcohol is employed as a preservative in various cosmetic and personal care products.
Phenethyl alcohol helps extend the shelf life of these products by inhibiting the growth of bacteria and fungi.
Phenethyl alcohol can be synthesized chemically through various methods, including the reduction of phenylacetic acid or the hydration of styrene.
Synthetic phenethyl alcohol is often used in the fragrance industry when a cost-effective and consistent source is needed.
Phenethyl alcohol can act as a solvent for various substances, which adds to Phenethyl alcohol versatility in different industrial applications.
Phenethyl alcohol is generally considered safe for use in cosmetics and personal care products when used in accordance with regulations.
However, like any chemical, Phenethyl alcohol should be handled with care, and Phenethyl alcohol concentration in formulations should comply with safety guidelines.
Phenethyl alcohol is the main component of rose oils obtained from rose blossoms.
Phenethyl alcohol occurs in smaller quantities in neroli oil, ylang-ylang oil, carnation oil, and geranium oils.
Since the alcohol is rather soluble in water, losses occur when essential oils are produced by steam distillation.
Phenethyl alcohol is a colorless liquid with a mild rose odor.
Phenethyl alcohol can be dehydrogenated catalytically to phenylacetaldehyde and oxidized to phenylacetic acid (e.g.,with chromic acid).
Phenethyl alcohol is fatty acid esterswith lowermolecularmass, as well as some alkyl ethers, are valuable fragrance and flavor substances.
Phenylethyl Alcohol is found in almond.
Phenethyl alcohol is a component of ylang-ylang oil.
Phenethyl alcohol is a flavouring ingredient.
Phenethyl alcohol is also called P-phenethyl alcohol, p-phenyl ethyl alcohol, 2-phenyl ethanol, benzeneethanol, benzyl carbinol, and p-hydroxyethylben.
Phenethyl alcohol is a colorless, transparent, slightly viscous liquid with a sharp, burning taste.
Phenethyl alcohol has a floral odor with a rose.
The molecular weight of Phenethyl alcohol is 122.1 7.
Phenethyl alcohol has a specific gravity of 1.0202 at 20°C (compared with water at 4°C) and a specific gravity of 1.01 7 to 1.01 9 at 25°C (compared with water at 25°C).
The boiling point of Phenethyl alcohol at 750 mm Hg is 219 to 221″C, at 14 mm Hg is 104″C, at 12 mm Hg is 98 to 1 OO”C, and at 10 mm Hg is 97.4″C.
The freezing point of Phenethyl alcohol is -27°C.
The alcohol is combustible, and Phenethyl alcohol flash point is 102.2″C.
The index of refraction for Phenethyl alcohol at 20°C for sodium light is 1.530 to 1.534.(2~4-6)
Phenethyl alcohol is very soluble in alcohol and ether.
Phenethyl alcohol is also soluble in fixed oils, glycerol, and propylene glycol and is slightly soluble in mineral oil.
A 2-ml sample of Phenethyl alcohol will dissolve in 100 ml of water after thorough Exposure to air may cause a slight oxidation of Phenethyl alcohol.
Phenethyl alcohol can be oxidized by acids and other oxidants, and oxidation in the presence of air is accelerated by heat.
Phenethyl alcohol is stable in colorless glass ampules at room temperature or in full opaque containers stored at 4 to 27°C for up to 1 year.
Phenethyl alcohol is absorbed by polyethylene c~ntainers.
Phenethyl alcohol occurs naturally in the environment.
Phenethyl alcohol is produced by microorganisms, plants, and animals.
Phenethyl alcohol has been found as the free alcohol oresterified in a number of natural essential oils, and in food, spices, and tobacco.
Phenethyl alcohol is used as a preservative ingredient in some soaps, and is also used in cosmetics, personal care products and food production for creating floral-rose fragrances and flavours.
Phenethyl alcohol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.
The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.
The resulting product is then purified to obtain Phenethyl Alcohol.
Phenethyl alcohol is a phenethyl alcohol that prevents or retards bacterial growth, and thus protects cosmetics and personal care products from spoilage.
Phenethyl alcohol is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence.
Phenethyl alcohol is a natural and multifunctional ingredient with a pleasant floral odor.
Due to Phenethyl alcohol excellent antimicrobial properties Phenethyl alcohol is used in cosmetics as a preservative booster to reduce traditional preservative use.
Contrarily to organic salt preservatives which require a low pH for optimum action, Phenethyl alcohol is pH independent.
Phenethyl alcohol is efficient in a broad pH range and heat stable.
For this reason, Phenethyl alcohol can be used in all kinds of products in cosmetics and perfumery, as a deodorant active and for alternative preservation.
Phenethyl alcohol is soluble in water and in most organic solvents.
Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group group attached to OH.
Phenethyl alcohol is a colourless liquid that is slightly soluble in water, but miscible with most organic solvents.
Incompatible with oxidizing agents and protein, e.g. serum.
Phenethyl alcohol is partially inactivated by polysorbates, although this is not as great as the reduction in antimicrobial activity that occurs with parabens and polysorbates.
Purify the ethanol by shaking Phenethyl alcohol with a solution of ferrous sulfate, and the alcohol layer is washed with distilled water and fractionally distilled.
Phenethyl alcohol was not mutagenic in bacterial assays, nor did Phenethyl alcohol increase the number of sister chromatid exchanges in human lymphocytes.
Phenethyl alcohol can also be prepared by the reaction between phenylmagnesium bromide and ethylene oxide:
C6H5MgBr + CH2CH2O → C6H5CH2CH2OMgBr
C6H5CH2CH2OMgBr + H+ → C6H5CH2CH2OH + MgBr+
Phenethyl alcohol can also be produced by biotransformation from L-phenylalanine using immobilized yeast Saccharomyces cerevisiae.
Phenethyl alcohol is also possible to produce phenethyl alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF.
Phenethyl alcohol is found in extract of rose, carnation, hyacinth, Aleppo pine, orange blossom, ylang-ylang, geranium, neroli, and champaca.
Phenethyl alcohol is also used as a preservative in soaps due to Phenethyl alcohol stability in basic conditions.
Phenethyl alcohol is of interest due to its antimicrobial properties.
Besides being found in essential oils of plants, phenethyl alcohol is a natural component of some fruits.
Phenethyl alcohol contributes to the characteristic aroma of certain fruits like apples and strawberries.
There is ongoing research into the potential therapeutic properties of phenethyl alcohol.
Some studies suggest that Phenethyl alcohol may have anti-inflammatory and antioxidant effects.
However, more research is needed to fully understand Phenethyl alcohol potential medical applications.
Phenethyl alcohol is used in various industrial processes.
For example, Phenethyl alcohol can be utilized as a precursor in the synthesis of other chemicals, including pharmaceuticals and agrochemicals.
Phenethyl alcohol is present in trace amounts in wine and is considered one of the volatile compounds that contribute to the overall aroma and flavor profile of the wine.
In perfumery, phenethyl alcohol is often used in combination with other aromatic compounds to create complex and well-balanced fragrances.
Phenethyl alcohol is mild and floral scent makes Phenethyl alcohol a versatile ingredient in fragrance formulations.
The use of phenethyl alcohol is subject to regulations and guidelines set by regulatory authorities in different countries.
Phenethyl alcohol is important for industries to comply with these regulations to ensure the safety and proper labeling of products containing this compound.
Phenethyl alcohol is relatively stable, but like many chemicals, Phenethyl alcohol can degrade over time, especially when exposed to light and air.
Proper storage conditions, such as keeping Phenethyl alcohol in a cool and dark place, are important to maintain Phenethyl alcohol quality.
The environmental impact of phenethyl alcohol depends on factors such as Phenethyl alcohol source (natural or synthetic) and the specific application.
In general, when used responsibly and in accordance with regulations, Phenethyl alcohol impact on the environment is considered minimal.
Uses of Phenethyl alcohol:
Phenethyl alcohol is qualitatively and quantitatively one of the most important fragrance substances that belongs to the class of araliphatic alcohols.
Phenethyl alcohol is used frequently and in large amounts as a fragrance material.
Phenethyl alcohol is a popular component in rose-type compositions, but Phenethyl alcohol is also used in other blossom notes.
Phenethyl alcohol is stable to alkali and, therefore, ideally suited for use in soap perfumes.
Phenethyl alcohol is used to mask odor and also as a preservative.
Phenethyl alcohol may be employed in the pharmaceutical industry as an ingredient in certain drug formulations.
Phenethyl alcohol is antimicrobial properties can contribute to the stability and preservation of pharmaceutical products.
The mild and pleasant scent of Phenethyl alcohol makes it suitable for use in insect repellents.
Phenethyl alcohol can be included in formulations to improve the overall fragrance of these products.
Phenethyl alcohol is sometimes used in the production of scented candles and air fresheners to impart a floral fragrance, enhancing the ambiance of living spaces.
Beyond cosmetics, Phenethyl alcohol is often included in various personal care products such as shampoos, conditioners, and body lotions for Phenethyl alcohol fragrance and preservative properties.
Due to Phenethyl alcohol solvent properties, Phenethyl alcohol can be used in the textile industry for processes like dyeing and finishing fabrics.
Phenethyl alcohol may be found in a range of household products, including cleaning solutions, fabric softeners, and laundry detergents, where Phenethyl alcohol antimicrobial properties contribute to product preservation.
In microbiology labs, Phenethyl alcohol is sometimes used as a disinfectant or as part of media formulations for culturing microorganisms.
Phenethyl alcohol’s antimicrobial properties make it a potential candidate for use in food packaging materials to inhibit the growth of microorganisms and extend the shelf life of packaged foods.
Phenethyl alcohol can be found in hair care products such as shampoos, conditioners, and styling products due to Phenethyl alcohol pleasing fragrance and preservative properties.
Phenethyl alcohol is sometimes used in the production of herbal extracts and tinctures, contributing to the overall aroma of the final product.
The antimicrobial properties of phenethyl alcohol make it a suitable ingredient in liquid soaps and body washes, helping to keep the products free from harmful microorganisms.
Phenethyl alcohol may be included in some mouthwashes and oral care products for Phenethyl alcohol antimicrobial effects and to enhance Phenethyl alcohol’s overall scent.
Some pet grooming products, such as shampoos and conditioners, may contain Phenethyl alcohol for its fragrance and preservative qualities.
Phenethyl alcohol can be found in floral waters and hydrosols, contributing to the aromatic properties of these products.
Phenethyl alcohol is used in the formulation of room sprays and air fresheners to provide a pleasant and long-lasting fragrance.
In niche and artisanal perfumery, where unique and specialized fragrances are crafted, phenethyl alcohol is valued for its floral and versatile characteristics.
In the production of botanical extracts used in skincare and cosmetic formulations, phenethyl alcohol may be employed for its aromatic qualities.
Some agricultural products, such as certain plant-based insecticides or repellents, may utilize phenethyl alcohol for its pleasant scent.
In the production of natural and organic cosmetic and personal care products, phenethyl alcohol is sometimes favored for its natural origin and pleasant fragrance.
Some niche and specialty food and beverage products may incorporate phenethyl alcohol for its unique floral and sweet aroma.
Phenethyl alcohol can be found in nail polishes, nail polish removers, and other nail care products due to Phenethyl alcohol fragrance and potential antimicrobial benefits.
Phenethyl alcohol is used in both aqueous and alcoholic perfume formulations, contributing to the fragrance stability in various types of perfumes.
In the formulation of biodegradable and environmentally friendly cleaners, phenethyl alcohol may be used for its cleaning properties and mild scent.
Some lotions and moisturizers may include phenethyl alcohol as part of their formulation for its preservative properties and fragrance.
Due to its antimicrobial properties, phenethyl alcohol may be found in antiseptic solutions used for skin disinfection.
In certain industrial applications, phenethyl alcohol can be used as a solvent in UV-curable coatings, contributing to the coating’s formulation and properties.
Phenethyl alcohol might be included in grooming sprays for pets to provide a pleasant scent and potentially help in controlling odors.
Some dental products, such as mouth rinses and dental gels, may contain phenethyl alcohol for its potential antimicrobial effects and fragrance.
Beyond Phenethyl alcohol use as a flavoring agent in the food industry, phenethyl alcohol is sometimes employed in the creation of floral and fruity flavorings for various food products.
In some culinary applications, phenethyl alcohol might be used to enhance the aroma and flavor of specific dishes or desserts.
Phenethyl alcohol is used as a preservative in cleansers, toners, moisturizers, and other cosmetic formulations.
Phenethyl alcohol helps in extending the shelf life of products and protects against harmful microorganisms.
Additionally, the skin conditioning properties of Phenethyl alcohol make it a popular ingredient in moisturizers and other skincare products
Cosmetic products:
Apart from acting as a preservative, Phenethyl alcohol is commonly used as a fragrance ingredient, adding a floral scent to cosmetic products.
Phenethyl alcohol can be found in a wide range of cosmetics, including foundations, blushes and eye shadows.
Phenethyl alcohol is used in food flavors, especially in honey, bread, apple, rose flavor and so on.
Phenethyl alcohol is used in tobacco flavors.
Phenethyl alcohol is used for blending rose essential oil and all kinds of fragrance, such as jasmine, lilac, and orange blossom fragrance, etc.
Phenethyl alcohol is used as an additive in cigarettes.
Phenethyl alcohol is a common ingredient in the fragrance and perfume industry.
Phenethyl alcohol is sweet, floral scent, reminiscent of roses, makes Phenethyl alcohol a popular choice for adding a rosy note to perfumes and personal care products.
In the food industry, phenethyl alcohol is used as a flavoring agent to impart a sweet and floral taste to certain products.
Phenethyl alcohol can be found in various food and beverage items.
Due to Phenethyl alcohol antimicrobial properties, phenethyl alcohol is used as a preservative in cosmetics, skincare products, and toiletries.
Phenethyl alcohol helps prevent the growth of bacteria and fungi, extending the shelf life of these products.
Phenethyl alcohol serves as a solvent in industrial processes, contributing to Phenethyl alcohol versatility.
Phenethyl alcohol can be used in the synthesis of various chemicals, including pharmaceuticals and agrochemicals.
While still being explored, research suggests that phenethyl alcohol may have potential therapeutic properties.
Phenethyl alcohol has been studied for its anti-inflammatory and antioxidant effects, but more research is needed to confirm these findings.
Natural phenethyl alcohol found in some fruits contributes to the characteristic aroma and flavor of certain foods, including apples and strawberries.
Phenethyl alcohol is present in trace amounts in wine and contributes to Phenethyl alcohol overall aroma and flavor profile.
Phenethyl alcohol is considered one of the volatile compounds influencing the sensory characteristics of wine.
The antimicrobial properties of phenethyl alcohol make it a suitable ingredient in some household cleaning products, detergents, and disinfectants.
Phenethyl alcohol’s pleasant scent makes it suitable for use in aromatherapy products, such as essential oil blends or diffuser oils.
Phenethyl alcohol is used in research and development laboratories, often as a reference compound or as a starting material in chemical synthesis.
Phenethyl alcohol is used as an antimicrobial preservative in nasal, ophthalmic, and otic formulations at 0.25–0.5% v/v concentration; Phenethyl alcohol is generally used in combination with other preservatives.
Phenethyl alcohol has also been used on its own as an antimicrobial preservative at concentrations up to 1% v/v in topical preparations.
At this concentration, mycoplasmas are inactivated within 20 minutes, although enveloped viruses are resistant.
Phenethyl alcohol is also used in flavors and as a perfumery component, especially in rose perfumes.
Production of Phenethyl alcohol:
Many syntheticmethods are known for preparing Phenethyl alcohol; the following are currently of industrial importance:
1) Friedel–Crafts reaction of benzene and ethylene oxide:
In the presence of molar quantities of aluminum chloride, ethylene oxide reacts with benzene to give an addition product, which is hydrolyzed to phenylethyl alcohol:
Friedel–Crafts reaction of benzene and ethylene oxide.
Formation of by-products, such as 1,2-diphenylethane, is largely avoided by using an excess of benzene at low temperature.
Special purification procedures are required to obtain a pure Phenethyl alcohol that is free of chlorine and suitable for use in perfumery.
2) Hydrogenation of styrene oxide:
Excellent yields of Phenethyl alcohol are obtainedwhen styrene oxide is hydrogenated at low temperature, using Raney nickel as a catalyst and a small amount of sodium hydroxide.
Storage of Phenethyl alcohol:
Phenethyl alcohol is stable in bulk, but is volatile and sensitive to light and oxidizing agents.
Phenethyl alcohol is reasonably stable in both acidic and alkaline solutions.
Aqueous solutions may be sterilized by autoclaving.
If stored in low-density polyethylene containers, Phenethyl alcohol may be absorbed by the containers.
Losses to polypropylene containers have been reported to be insignificant over 12 weeks at 30°C.
The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.
Safety Profile of Phenethyl alcohol:
Moderately toxic by ingestion and skin contact.
Phenethyl alcohol a skin and eye irritant.
Experimental teratogenic effects.
Other experimental reproductive effects.
Causes severe central nervous system injury to experimental animals.
Combustible when exposed to heat or flame; can react with oxidzing materials.
When heated to decomposition Phenethyl alcohol emits acrid smoke and irritating fumes
Phenethyl alcohol is generally regarded as a nontoxic and nonirritant material.
However, at the concentration used to preserve eye-drops (about 0.5% v/v) or above, eye irritation may occur.
Phenethyl alcohol can be produced through various methods, including chemical synthesis and natural extraction from plants such as rose and jasmine.
The most common method involves the reduction of benzaldehyde with sodium borohydride in the presence of a catalyst.
The resulting Phenethyl alcohol is then purified to obtain Phenethyl Alcohol.
Identifiers of Phenethyl alcohol:
CAS Number: 60-12-8
Molecular Formula: C8H10O
Molecular Weight: 122.16
EINECS Number: 200-456-2
Merck: 14,7224
JECFA Number: 987
BRN: 1905732
Stability: Stable. Substances to be avoided include strong acids and strong oxidizing agents. Combustible.
InChIKey: WRMNZCZEMHIOCP-UHFFFAOYSA-N
LogP: 1.50
Properties of Phenethyl alcohol:
Melting point: -27 °C (lit.)
Boiling point: 219-221 °C/750 mmHg (lit.)
Density: 1.020 g/mL at 20 °C (lit.)
vapor density: 4.21 (vs air)
vapor pressure: 1 mm Hg ( 58 °C)
refractive index: n20/D 1.5317(lit.)
FEMA: 2858 | PHENETHYL ALCOHOL
Flash point: 216 °F
storage temp.: Store below +30°C.
solubility: Miscible with chloroform.
form: Liquid
pka: 15.17±0.10(Predicted)
color: Clear colorless
Odor: floral odor of roses
PH: 6-7 (20g/l, H2O, 20℃)
explosive limit 1.4-11.9%(V)
Odor Type: floral
Water Solubility: 20 g/L (20 ºC)
Dielectric constant: 13.0（20℃）