SODIUM ASCORBATE

Sodium ascorbate is an essential nutrient with antioxidant properties, helping to protect cells from oxidative stress and supporting various bodily functions, including collagen synthesis, immune function, and wound healing.

Sodium ascorbate is preferred by some people for its less acidic nature, making it gentler on the stomach.

Sodium ascorbate neutralizes free radicals, which are unstable molecules that can damage cells, proteins, and DNA, leading to premature aging, chronic diseases, and even cancer.

CAS Number: 134-03-2

EC Number: 205-126-1

Molecular Formula: C6H7NaO6

Molecular Weight: 198.11

Synonyms: SODIUM ASCORBATE, 134-03-2, L-Ascorbic acid sodium salt, Sodium L-ascorbate, Vitamin C sodium, Monosodium L-ascorbate, Ascorbicin, Ascorbic acid sodium salt, Natrii ascorbas, Iskia-C, Natri-C, Ascorbate de sodium, Sodascorbate, (+)-Sodium L-ascorbate, L-Ascorbic acid, monosodium salt, Vitamin C Sodium Salt, Vitamin C, sodium salt, ascorbate, Ascorbin, Cevalin, MFCD00082340, 3-Oxo-L-gulofuranolactone sodium, INS NO.301, L(+)-Ascorbic acid sodium salt, INS-301, S033EH8359, L-Ascorbic acid (sodium salt), DTXSID0020105, E-301, CHEBI:113451, l-Ascorbate, sodium, Sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Cebitate, Aminofenitrooxon, sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate, sodium (L)-ascorbate, sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, SODIUM ASCORBATE (II), SODIUM ASCORBATE [II], SODIUM ASCORBATE (MART.), SODIUM ASCORBATE [MART.], sodiumascorbate, SODIUM ASCORBATE (USP-RS), SODIUM ASCORBATE [USP-RS], Ascorbato sodico, Ascorbato sodico [DCIT], sodium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate, SODIUM ASCORBATE (EP MONOGRAPH), SODIUM ASCORBATE [EP MONOGRAPH], SODIUM ASCORBATE (USP MONOGRAPH), SODIUM ASCORBATE [USP MONOGRAPH], Monosodium Ascorbate, Natrii ascorbas [INN-Latin], Ascorbic acid sodium derivative, CCRIS 3291, HSDB 694, HBL 508, L-Ascorbic acid sodium, Ascorbate de sodium [INN-French], EINECS 205-126-1, Sodium ascorbate [USP:INN], UNII-S033EH8359, Sodium derivative of 3-oxo-L-gulofuranolactone, Ascorbate, Sodium, sodium (2R)-2-((1S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Sodium ascorbate; Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, (+)-Sodium L-ascorbate;Vitamin C sodium salt;Sodium L-ascorbate, E301, sodium L-ascorbate salt, VITA-JEC C, EC 205-126-1, SCHEMBL3745, ASK-P 10KR, DTXCID60105, L(+)Ascorbic acid sodium salt, SODIUM ASCORBATE [FCC], SODIUM ASCORBATE [INN], CHEMBL591665, HY-B0166AR, SODIUM ASCORBATE [HSDB], SODIUM ASCORBATE [VANDF], HY-B0166A, SODIUM ASCORBATE [WHO-DD], L-Ascorbic Acid Sodium Salt,(S), Tox21_300556, AKOS015895058, L-Ascorbic acid, sodium salt (1:1), SODIUM ASCORBATE [ORANGE BOOK], ASCORBIC ACID SODIUM SALT [MI], CS-6063, DB14482, 3-Keto-L-gulofuranlactone sodium enolate, NCGC00254355-01, BP-30077, CAS-134-03-2, DA-77918, L-Ascorbic acid (sodium salt) (Standard), A0539, E80761, EN300-221566, A806721, Q424551, J-006471, 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate, Z1255486556, sodium (2R)-2-[(1S)-1,2-bis(oxidanyl)ethyl]-4-oxidanyl-5-oxidanylidene-2H-furan-3-olate, Sodium(R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, ASCORBIC ACID SODIUM SALT;L(+)-ASCORBIC ACID SODIUM SALT;L-ASCORBIC ACID SODIUM SALT;L-ASCORBIC ACID NA-SALT;SODIUMASCORBATE,GRANULAR,FCC;SODIUMASCORBATE,GRANULAR,USP;SODIUMASCORBATE,POWDER,USP;SODIUM ASCORBATE (VC-NA) AND ITS DIRECTLY-COMPRESSION GRANULE

Sodium ascorbate is a salt form of vitamin C (ascorbic acid) and is commonly used as a dietary supplement and food additive.

Sodium ascorbate is an essential nutrient with antioxidant properties, helping to protect cells from oxidative stress and supporting various bodily functions, including collagen synthesis, immune function, and wound healing.

Sodium ascorbate is often preferred over ascorbic acid because it is less acidic, which makes it easier on the stomach, particularly for people who experience discomfort from the acidity of pure vitamin C.

In its role as a supplement, sodium ascorbate is used to prevent and treat vitamin C deficiencies, such as scurvy, and to support overall health by boosting the immune system, promoting healthy skin, and aiding in the absorption of iron from plant-based foods.

Sodium ascorbate is a water-soluble compound, meaning that it is easily dissolved in water and can be absorbed efficiently by the body when taken orally.

In food processing, sodium ascorbate is often used as an antioxidant to prevent the oxidation of fats and oils, thereby extending the shelf life of products.

Sodium ascorbate also functions as a preservative, maintaining the color, flavor, and nutritional value of foods.

Sodium ascorbate may be added to packaged foods, beverages, and cosmetics to enhance product stability and prevent spoilage.

Due to its lower acidity, Sodium ascorbate is also more versatile for incorporation into a variety of formulations, including those intended for sensitive stomachs or specific dietary needs.

Sodium ascorbate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum. Sodium ascorbate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. The compound is also beneficial in various medical and cosmetic applications. For instance, in topical skincare products, sodium ascorbate can help to brighten the skin, reduce the appearance of fine lines, and promote a more youthful complexion by neutralizing free radicals that damage skin cells. In medical settings, sodium ascorbate has been explored as an adjunctive treatment for certain health conditions, including cancer, due to its potential to support the immune system and enhance the effectiveness of other treatments. As with any supplement or ingredient, Sodium ascorbate is essential to adhere to recommended dosages of sodium ascorbate to avoid potential side effects, including gastrointestinal discomfort or interactions with certain medications. Overall, sodium ascorbate is a versatile, effective, and well-tolerated form of vitamin C that plays a vital role in maintaining health and wellness across various sectors, from nutrition to skincare and beyond. Sodium ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C), which is approved for use as a food additive in many countries.  Sodium ascorbate is consisted of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry.  Sodium ascorbate contains a L-ascorbate. In this mixture, Sodium ascorbate acts as a buffer, creating a less acidic supplement than those made entirely from vitamin C.  Sodium ascorbate can be easier to tolerate if the digestive system is sensitive to acid.  As a vitamin C supplement, Sodium ascorbate provides both sodium and vitamin C for human body, which is effective to prevent or treat vitamin C deficiency.  Besides, studies have shown that taking sodium ascorbate is helpful with cancer prevention and treatment. Sodium ascorbate occurs as a white or slightly yellow-colored, practically odorless, crystalline powder with a pleasant saline taste. Sodium ascorbate is the sodium salt of ascorbic acid, commonly known as Vitamin C.  Sodium ascorbate is a water-soluble compound that offers the same antioxidant benefits as pure Vitamin C, helping to neutralize harmful free radicals in the body.  Sodium ascorbate is often used in food preservation and as a dietary supplement, particularly in cases where individuals may have difficulty tolerating the acidity of pure ascorbic acid.  Sodium ascorbate is preferred by some people for its less acidic nature, making it gentler on the stomach. Sodium ascorbate is a compound with a wide array of uses, primarily due to its potent antioxidant properties.  As the Sodium ascorbate salt of ascorbic acid (Vitamin C), it possesses the same health benefits as Vitamin C, but in a more stable and less acidic form.  This makes Sodium ascorbate a preferred choice in both medical and commercial applications, particularly when the goal is to provide a milder alternative to pure ascorbic acid. In addition to Sodium ascorbate's use in supplements and food, sodium ascorbate has various applications in the pharmaceutical and cosmetic industries, where it is used for its antioxidant properties.  Sodium ascorbate helps stabilize formulations and prevent oxidation in products like skincare treatments.  Sodium ascorbate is also used in the treatment of scurvy, a disease caused by Vitamin C deficiency, and in various laboratory and research settings where it acts as a reducing agent. Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).  The molecular formula of this chemical compound is C6H7NaO6.  As the sodium salt of ascorbic acid, it is known as a mineral ascorbate.  Sodium ascorbate has not been demonstrated to be more bioavailable than any other form of vitamin C supplement. Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium). As a food additive, Sodium ascorbate has the E number E301 and is used as an antioxidant and an acidity regulator.  Sodium ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand. In in vitro studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible. Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of sodium hydroxide or sodium bicarbonate in water.  After cessation of effervescence, the sodium ascorbate is precipitated by the addition of isopropanol. Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).  The molecular formula of this chemical compound is C6H7NaO6.  As the sodium salt of ascorbic acid, it is known as a mineral ascorbate.  Sodium ascorbate has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.  Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).  As a food additive, Sodium ascorbate has the E number E301 and is used as an antioxidant and an acidity regulator.  Sodium ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand.  In in vitro studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible. Sodium ascorbate is a versatile and widely used compound, primarily known for its role as an antioxidant and a stabilizing agent.  As a salt of ascorbic acid, it combines the benefits of Vitamin C with the additional advantage of being less acidic than its parent compound, making it easier for people to tolerate, especially those with sensitive stomachs.  This property makes it a preferred choice in both food and pharmaceutical products, where a gentler, less acidic form of Vitamin C is desired. In the medical field, sodium ascorbate plays an important role in supporting immune function.  Sodium ascorbate enhances the body’s ability to fight infections by boosting the production of white blood cells, which are crucial in defending against pathogens.  In addition to its immune-boosting properties, sodium ascorbate is involved in the synthesis of collagen, an essential protein for the skin, cartilage, tendons, and bones.  This function makes it vital for wound healing and tissue repair.  Regular intake of sodium ascorbate is associated with improved skin health, stronger bones, and enhanced muscle function. Beyond its immune system support, sodium ascorbate is also known for its role in managing oxidative stress.  Sodium ascorbate neutralizes free radicals, which are unstable molecules that can damage cells, proteins, and DNA, leading to premature aging, chronic diseases, and even cancer.  By reducing oxidative damage, sodium ascorbate may help mitigate the risk of various health issues related to aging, such as cardiovascular disease, arthritis, and neurodegenerative disorders like Alzheimer’s disease. An equivalent amount of sodium bicarbonate is added to a solution of ascorbic acid in water.  Following the cessation of effervescence, the addition of propan-2-ol precipitates sodium ascorbate. Materials in this group are generally soluble in water.  The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids.  These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.  They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Incompatible with oxidizing agents, heavy metal ions, especially copper and iron, methenamine, sodium nitrite, sodium salicylate, and theobromine salicylate.  The aqueous solution is reported to be incompatible with stainless steel filters. In the food industry, sodium ascorbate is commonly used as a preservative to prevent oxidation and extend shelf life.  Sodium ascorbate is effective in preventing the browning of fruits and vegetables, preserving the color and nutritional content of the food.  Additionally, Sodium ascorbate is utilized in processed meats to maintain freshness and prevent spoilage.  Sodium ascorbate's antioxidant activity also contributes to the prevention of rancidity in oils and fats. Sodium ascorbate is widely used in the field of medicine and health supplements.  Sodium ascorbate is an essential ingredient in many Vitamin C supplements, where it is often marketed as a less acidic alternative to pure ascorbic acid.  This makes it a popular choice for people who need to boost their Vitamin C intake but wish to avoid the discomfort that can sometimes accompany high doses of ascorbic acid.  In therapeutic doses, sodium ascorbate can help with the prevention and treatment of scurvy, support the immune system, and promote skin health by aiding in collagen formation. In addition to its health benefits, sodium ascorbate has various applications in the cosmetic industry.  Sodium ascorbate's antioxidant properties help in the formulation of skin-care products, as it can neutralize free radicals and protect the skin from oxidative stress.  This makes it valuable in products that aim to prevent premature aging, reduce the appearance of wrinkles, and improve the overall appearance of the skin. Furthermore, sodium ascorbate plays a critical role in scientific research and laboratory settings.  Sodium ascorbate is used as a reducing agent in various chemical reactions and experiments.  Researchers rely on Sodium ascorbate's ability to reduce metal ions and other compounds, facilitating the completion of reactions in both biochemical and synthetic applications.  This makes sodium ascorbate indispensable in numerous research disciplines, including biotechnology, medicine, and chemistry. Overall, sodium ascorbate is a widely applicable compound with numerous uses in health, food preservation, cosmetics, and scientific research.  Sodium ascorbate's mild acidity, combined with its strong antioxidant properties, makes it a valuable ingredient across many industries. In the cosmetic industry, sodium ascorbate is incorporated into skincare formulations due to its ability to protect the skin from environmental damage.  Sodium ascorbate's antioxidant properties help to prevent UV-induced skin damage, reduce pigmentation, and promote a more even skin tone.  As an essential element in collagen synthesis, sodium ascorbate also contributes to skin elasticity, reducing the appearance of wrinkles and promoting a youthful complexion.  Additionally, sodium ascorbate’s ability to inhibit melanin production is often harnessed in products designed to lighten dark spots and hyperpigmentation. The pharmaceutical industry has also embraced sodium ascorbate for its versatile applications.  Sodium ascorbate is frequently used in intravenous (IV) treatments, particularly for high-dose Vitamin C therapies.  This form of administration allows for a higher concentration of Vitamin C to be delivered directly into the bloodstream, offering potential benefits in cancer treatment, where it may help enhance the effectiveness of certain chemotherapy drugs and reduce side effects.  Sodium ascorbate has also been explored as a treatment for viral infections, inflammation, and chronic fatigue syndrome. Sodium ascorbate’s role in food preservation is another significant application.  As a preservative, Sodium ascorbate extends the shelf life of perishable goods by preventing oxidation, which can cause spoilage and loss of nutrients.  Sodium ascorbate's ability to prevent browning in fruits and vegetables is especially important in the food industry, where maintaining both the aesthetic and nutritional quality of products is essential.  In meats, sodium ascorbate helps to inhibit the formation of harmful compounds like nitrosamines, which can form during the curing process.  Sodium ascorbate is also used to preserve the quality of beverages, such as fruit juices, where it helps retain both flavor and color. In addition to these well-known uses, sodium ascorbate is a crucial reagent in various scientific research fields.  In biochemistry, Sodium ascorbate serves as a reducing agent, assisting in redox reactions in both organic and inorganic chemistry.  Researchers use sodium ascorbate to stabilize compounds and prevent oxidation in sensitive reactions.  Sodium ascorbate also plays a role in laboratory tests, such as those used to measure the concentration of metal ions or other substances in a sample. Furthermore, sodium ascorbate’s potential benefits in environmental science are gaining attention.  Due to its reducing properties, Sodium ascorbate has been proposed as an eco-friendly option for environmental cleanup.  Researchers are exploring its use in the remediation of heavy metal contamination in water and soil, as Sodium ascorbate could help reduce harmful metal ions into less toxic forms, facilitating environmental restoration. In summary, sodium ascorbate is much more than just a supplement or food preservative.  Sodium ascorbate's ability to combat oxidative stress, support immune function, promote skin health, and even contribute to environmental sustainability underscores its significance across a variety of fields.  Sodium ascorbate continues to be a valuable tool in medicine, science, industry, and health. Uses of Sodium Ascorbate: Sodium ascorbate, the sodium salt of vitamin C, is a versatile compound with numerous applications in various industries. In the medical field, Sodium ascorbate is primarily used as a dietary supplement to prevent and treat vitamin C deficiencies, support immune function, and promote wound healing. As an antioxidant, Sodium ascorbate helps protect cells from oxidative stress, contributing to overall health and longevity. In food processing, sodium ascorbate serves as an effective preservative and antioxidant, extending shelf life by preventing the oxidation of fats and oils, while also maintaining the color, flavor, and nutritional value of products. Sodium ascorbate is commonly added to processed foods and beverages to boost their vitamin C content. In skincare, sodium ascorbate is valued for its ability to brighten the skin, reduce wrinkles, and promote collagen production, making it a popular ingredient in anti-aging and restorative products. Additionally, sodium ascorbate has been explored in medical treatments, including cancer therapy, where it may help enhance the effectiveness of other treatments and support immune health. Sodium ascorbate's industrial uses extend to the chemical and textile industries, where it serves as a reducing agent and aids in the stability of dyes. This wide range of uses underscores the importance of sodium ascorbate in enhancing health, preserving food, and supporting various manufacturing processes. Sodium Ascorbate is an antioxidant that is the sodium form of ascorbic acid.  Sodium ascorbate is soluble in water and provides a nonacidic taste.  Sodium ascorbate readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant.  Sodium ascorbate is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. Sodium ascorbate is used as an antioxidant in pharmaceutical formulations, and also in food products where it increases the effectiveness of sodium nitrite against growth of Listeria monocytogenes in cooked meats.  Sodium ascorbate improves gel cohesiveness and sensory firmness of fiberized products regardless of vacuum treatment. Sodium ascorbate is also used therapeutically as a source of vitamin C in tablets and parenteral preparations. Sodium ascorbate is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets.  Most people who eat a normal diet do not need extra ascorbic acid. Low levels of vitamin C can result in a condition called scurvy.  Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss. Sodium ascorbate is needed to maintain the health of skin, cartilage, teeth, bone, and blood vessels.  Sodium ascorbate is also used to protect your body's cells from damage.  Sodium ascorbate is known as an antioxidant. Sodium ascorbate is commonly used as a supplement to provide Vitamin C in a more stomach-friendly form compared to pure ascorbic acid.  Sodium ascorbate helps in the prevention and treatment of scurvy, supports the immune system, and promotes overall health by enhancing collagen formation for skin, cartilage, tendons, and bones. Sodium ascorbate plays a crucial role in boosting immune function by stimulating white blood cell production and enhancing the body's defense against infections. As an antioxidant, sodium ascorbate neutralizes free radicals in the body, which helps reduce oxidative stress and may lower the risk of chronic diseases, including cardiovascular diseases and certain types of cancer. Sodium ascorbate is used as a preservative in food products to prevent oxidation, spoilage, and discoloration.  Sodium ascorbate helps maintain the freshness and nutritional content of foods, particularly in fruits, vegetables, and processed meats. Sodium ascorbate prevents the browning of fruits and vegetables, such as in apples, potatoes, and avocados, by inhibiting enzymatic browning, thus improving the appearance and shelf life of fresh produce. Sodium ascorbate is added to processed meats (like sausages and hot dogs) to prevent rancidity and the formation of harmful compounds like nitrosamines during the curing process. Sodium ascorbate helps preserve the flavor, color, and nutrient content of beverages like fruit juices and soft drinks, protecting them from oxidation. Sodium ascorbate is incorporated into many skincare formulations due to its ability to neutralize free radicals that contribute to skin aging.  Sodium ascorbate helps reduce the appearance of wrinkles and fine lines by stimulating collagen production and promoting skin elasticity. Sodium ascorbate is often used in skin care products aimed at brightening the complexion and reducing hyperpigmentation, such as dark spots or age spots, due to its ability to inhibit melanin production. As an antioxidant, sodium ascorbate helps protect the skin from oxidative damage caused by UV radiation, making it a valuable ingredient in sunscreen and sun care products. Sodium ascorbate is used in high-dose intravenous (IV) Vitamin C treatments, which are sometimes used in the treatment of cancer, chronic infections, and other conditions.  IV administration allows higher concentrations of Vitamin C to be delivered directly into the bloodstream, which may enhance the effectiveness of chemotherapy or other treatments. Sodium ascorbate has anti-inflammatory properties and can be used in medical treatments to reduce inflammation and support tissue repair. Due to its essential role in collagen synthesis, sodium ascorbate is used in treatments that aid in wound healing and tissue repair, as well as in improving skin and joint health. Sodium ascorbate is used as a reducing agent in laboratory research, particularly in biochemistry and organic chemistry.  Sodium ascorbate helps in the reduction of metal ions and is used in various redox reactions. In biochemical studies, sodium ascorbate is often employed to stabilize reactive compounds and prevent oxidation in sensitive experimental setups. Sodium ascorbate is used in synthetic chemistry, especially in the production of pharmaceutical compounds, by acting as a reducing agent in the creation of complex molecules. Sodium ascorbate has potential applications in environmental science, particularly in the remediation of heavy metal contamination.  Sodium ascorbate's reducing properties can help detoxify polluted environments by transforming harmful metal ions into less toxic forms. In industries where oxidation could compromise product quality (such as in plastics, rubbers, or oils), sodium ascorbate is sometimes used to stabilize materials and prolong their shelf life. Sodium ascorbate is sometimes added to animal feed to ensure that animals receive an adequate intake of Vitamin C, especially for species that do not produce it naturally.  Sodium ascorbate helps support immune health and overall well-being in livestock. Sodium ascorbate has a wide range of uses, both in the medical and food industries, as well as in skincare and other consumer products. Here are some of the key uses of sodium ascorbate: Dietary Supplement: Vitamin C Source: Sodium ascorbate is often used as a vitamin C supplement to help prevent and treat vitamin C deficiencies, such as scurvy. Sodium ascorbate is an essential nutrient that supports immune function, collagen production, and iron absorption. Immune Support: Sodium ascorbate boosts the immune system, helping the body fight infections and maintain general health. Antioxidant: As a powerful antioxidant, sodium ascorbate helps neutralize free radicals, protecting cells from oxidative stress and supporting overall health and longevity. Food Additive: Preservative: Sodium ascorbate is commonly used in food processing to prevent oxidation in fats and oils, thus extending the shelf life of products and preventing spoilage. Antioxidant: Sodium ascorbate helps preserve the color, flavor, and nutritional value of packaged foods and beverages. By preventing the oxidation of certain ingredients, Sodium ascorbate keeps the food fresh. Enhances Nutritional Value: Sodium ascorbate can be added to food products to enhance their vitamin C content, providing a dietary boost of this essential nutrient. Cosmetic and Skincare Products: Anti-aging Benefits: Sodium ascorbate is included in many skincare formulations because of its ability to brighten the skin, reduce the appearance of wrinkles and fine lines, and promote a more youthful complexion. Skin Repair: Sodium ascorbate helps to heal skin damage, including sunburn, by stimulating collagen production and reducing inflammation. Antioxidant Protection: In topical skincare products, sodium ascorbate helps protect skin cells from oxidative stress, which can contribute to premature aging and skin damage. Medical Applications: Adjunctive Cancer Treatment: Some research suggests that sodium ascorbate, as a form of vitamin C, may play a role in supporting cancer treatments by boosting the immune system and reducing oxidative damage caused by cancer therapies. Wound Healing: As an essential component in collagen formation, sodium ascorbate is used in some wound healing treatments to speed recovery and tissue repair. Iron Absorption: Sodium ascorbate can improve the absorption of non-heme iron from plant-based foods, helping individuals with iron deficiencies or anemia. Industrial Applications: Chemical Industry: Sodium ascorbate is sometimes used in chemical formulations as a reducing agent in various processes, including the reduction of metals and other compounds. Textile and Dyeing: Sodium ascorbate can be employed in the textile industry to reduce oxidation and improve dye stability. Consumer Uses: Sodium ascorbate is used in the following products: cosmetics and personal care products. Other release to the environment of Sodium ascorbate is likely to occur from: indoor use as processing aid. Widespread uses by professional workers: Sodium ascorbate is used in the following products: adsorbents. Sodium ascorbate is used in the following areas: scientific research and development. Other release to the environment of Sodium ascorbate is likely to occur from: indoor use as processing aid. Uses at industrial sites: Sodium ascorbate has an industrial use resulting in manufacture of another substance (use of intermediates). Sodium ascorbate is used for the manufacture of: chemicals. Release to the environment of Sodium ascorbate can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). Benefits of Sodium Ascorbate: Sodium ascorbate offers a variety of health and wellness benefits due to its high vitamin C content and antioxidant properties. Here are some of Sodium ascorbate's key benefits: Boosts Immune System: Sodium ascorbate plays a vital role in enhancing immune function, helping the body to fight infections and illnesses. Sodium ascorbate supports the production and function of white blood cells, which are essential for immune defense. Antioxidant Protection: As a powerful antioxidant, sodium ascorbate helps neutralize harmful free radicals in the body. This reduces oxidative stress and may lower the risk of chronic diseases such as heart disease, diabetes, and certain cancers. Supports Collagen Production: Vitamin C is essential for the synthesis of collagen, a protein that is crucial for skin, cartilage, tendons, ligaments, and blood vessels. Sodium ascorbate promotes healthy skin, reduces wrinkles, and supports joint and tissue health. Enhances Iron Absorption: Sodium ascorbate aids in the absorption of non-heme iron (iron from plant-based foods). This is especially beneficial for individuals with iron deficiencies or those following plant-based diets, as Sodium ascorbate helps prevent iron deficiency anemia. Wound Healing: By promoting collagen formation, sodium ascorbate accelerates the healing process of wounds and injuries. Sodium ascorbate is also helpful for the recovery of tissues after surgery or physical trauma. Skin Health: Sodium ascorbate is commonly used in skincare products for its ability to brighten the complexion, reduce dark spots, and diminish the signs of aging. Sodium ascorbate can also protect the skin from sun damage and reduce inflammation. Heart Health: The antioxidant effects of sodium ascorbate help reduce inflammation in the body, potentially lowering the risk of cardiovascular diseases by improving blood vessel function and reducing blood pressure. Preventing Scurvy: As a reliable source of vitamin C, sodium ascorbate is essential in preventing scurvy, a disease caused by a severe vitamin C deficiency. Symptoms include fatigue, swollen gums, and skin problems. Cancer Support: Some studies suggest that sodium ascorbate, as a form of vitamin C, may enhance cancer treatment by supporting the immune system and helping to reduce side effects of therapies like chemotherapy. Production The production of sodium ascorbate typically involves a chemical process that converts ascorbic acid (vitamin C) into its sodium salt form. The production process can be broken down into several key steps: Synthesis of Ascorbic Acid: Ascorbic acid is often synthesized through a chemical reaction known as the Reichstein process, which involves the hydrogenation of glucose to produce sorbitol, followed by a series of steps that convert sorbitol into ascorbic acid. This process has been widely used in the industrial production of vitamin C. Neutralization of Ascorbic Acid: Once ascorbic acid is produced, Sodium ascorbate is neutralized with a sodium source, typically sodium bicarbonate (baking soda) or sodium hydroxide (lye), to form sodium ascorbate. The neutralization reaction is as follows: C6HO6+NaOH→C6H7NaO6+H2O In this reaction, ascorbic acid (C6H8O6) reacts with sodium hydroxide (NaOH) to form sodium ascorbate (C6H7NaO6) and water. Purification: After the neutralization process, the sodium ascorbate solution may contain impurities such as residual sodium hydroxide, excess ascorbic acid, or by-products from the reaction. The solution is typically purified through filtration and crystallization to remove these impurities, ensuring a high-quality final product. Drying: The purified sodium ascorbate solution is then concentrated and dried to obtain the final powder or crystalline form of sodium ascorbate. This is typically done through spray drying or freeze-drying techniques, which help preserve the stability and effectiveness of the compound. Quality Control: The final sodium ascorbate product undergoes rigorous quality control testing to ensure that it meets required specifications for purity, potency, and safety. This may include tests for heavy metals, microbial contamination, and vitamin C content. Packaging and Distribution: Once the sodium ascorbate has passed quality control, Sodium ascorbate is packaged into containers, often in powder or granulated form, and distributed for use in dietary supplements, food products, pharmaceuticals, and cosmetics. Overall, the production of sodium ascorbate is a carefully controlled process that involves the synthesis of ascorbic acid, neutralization with sodium, purification, drying, and quality control. The resulting product is a stable, bioavailable form of vitamin C used in a wide range of applications. History of Sodium Ascorbate: The history of sodium ascorbate is closely tied to the development and discovery of vitamin C and its significance in human health. Here's a brief overview of Sodium ascorbate's historical context: Discovery of Vitamin C (Ascorbic Acid): The story of vitamin C begins in the 18th century with the observation that sailors who were deprived of fresh fruits and vegetables on long voyages often developed a disease known as scurvy. In 1747, British naval surgeon James Lind conducted experiments aboard ships and found that sailors who consumed citrus fruits such as oranges and lemons did not develop scurvy. This was the first indication that a specific nutrient, later identified as vitamin C, was essential for preventing the disease. Identification of Vitamin C: In the early 20th century, scientists began to isolate and identify the specific substance responsible for preventing scurvy. In 1928, Hungarian scientist Albert Szent-Györgyi is credited with discovering vitamin C, although he initially isolated the compound from paprika (a type of pepper) and not from citrus fruits. Szent-Györgyi’s discovery of ascorbic acid earned him the Nobel Prize in Physiology or Medicine in 1937. Synthesis of Vitamin C: Following the identification of vitamin C, researchers worked on synthesizing it for use as a supplement. In 1933, a team of scientists led by American chemist Tadeus Reichstein developed a method to synthesize ascorbic acid from glucose, known as the Reichstein process. This breakthrough allowed for the large-scale production of vitamin C and made it widely available for medical and commercial use. Development of Sodium Ascorbate: Ascorbic acid, while effective, is highly acidic, which can cause stomach discomfort when consumed in high doses. In response to this, researchers developed sodium ascorbate as an alternative, as Sodium ascorbate is a less acidic, more neutral form of vitamin C. The sodium salt of ascorbic acid was introduced as a way to improve the bioavailability and tolerance of vitamin C supplements, especially for people who experienced gastrointestinal issues with ascorbic acid. Commercialization and Use: By the mid-20th century, sodium ascorbate became widely used in the food industry as a preservative and antioxidant, in addition to its use as a dietary supplement. Sodium ascorbate also found a role in pharmaceutical formulations and topical skincare products, where its antioxidant properties helped prevent skin aging and supported wound healing. Ongoing Research and Applications: Over time, research into the benefits of vitamin C, including sodium ascorbate, has continued to expand. Studies have investigated its role in immune function, cancer support, cardiovascular health, and skin care. Sodium ascorbate is now recognized as a stable, non-acidic alternative to pure ascorbic acid, widely used in the healthcare, food, and cosmetic industries. In summary, the history of sodium ascorbate is rooted in the discovery of vitamin C, its importance in preventing scurvy, and the subsequent development of its synthetic forms. The creation of sodium ascorbate allowed for the easier, more tolerable consumption of vitamin C and has cemented its place as a key compound in nutrition, medicine, and consumer products. Handling and Storage of Sodium Ascorbate: Precautions for safe handling: Avoid inhalation of vapour or mist.   Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place.  Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials   Stability and Reactivity of Sodium Ascorbate: Chemical stability: Stable under recommended storage conditions. Incompatible materials: Strong oxidizing agents: Hazardous decomposition products: Hazardous decomposition products formed under fire conditions.  Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.   Disposal considerations: Waste treatment methods: Offer surplus and non-recyclable solutions to a licensed disposal company.  Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging: Dispose of as unused product First Aid Measures of Sodium Ascorbate: General advice: Consult a physician.  Show this safety data sheet to the doctor in attendance. Move out of dangerous area.   If inhaled: If breathed in, move person into fresh air.  If not breathing, give artificial respiration. Consult a physician. In case of skin contact: Take off contaminated clothing and shoes immediately.  Wash off with soap and plenty of water. Consult a physician.   In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Continue rinsing eyes during transport to hospital.   If swallowed: Do NOT induce vomiting.  Never give anything by mouth to an unconscious person.  Rinse mouth with water.  Consult a physician.   Firefighting Measures of Sodium Ascorbate: Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas   Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Accidental Release Measures of Sodium Ascorbate: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment.    Avoid breathing vapours, mist or gas.  Evacuate personnel to safe areas.   Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.   Methods and materials for containment and cleaning up: Soak up with inert absorbent material and dispose of as hazardous waste.  Keep in suitable, closed containers for disposal. Exposure Controls/Personal Protection of Sodium Ascorbate: Control parameters: Components with workplace control parameters. Contains no substances with occupational exposure limit values. Exposure controls: Appropriate engineering controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.   Personal protective equipment: Eye/face protection: Tightly fitting safety goggles.  Faceshield (8-inch minimum).  Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).   Skin protection: Handle with gloves.  Gloves must be inspected prior to use.  Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with Sodium ascorbate.  Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.  Wash and dry hands.   Full contact: Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0.11 mm Break through time: 480 min Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M) Sodium ascorbate should not be construed as offering an approval for any specific use scenario.   Body Protection: Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.    If the respirator is the sole means of protection, use a full-face supplied air respirator.  Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure: Prevent further leakage or spillage if safe to do so.  Do not let product enter drains. Discharge into the environment must be avoided. Identifiers of Sodium Ascorbate: CAS Number: 134.03.2  CHEBI:113451  ChEMBL: ChEMBL591665  ECHA InfoCard: 100.004.661 EC Number 205.126.1 E number: E301 (antioxidants, ...) KEGG: D05853  PubChem CID: 23667548 RTECS number: CI7671000 UNII: S033EH8359  CompTox Dashboard (EPA): DTXSID0020105 CAS Number: 134-03-2 E Number: E301 PubChem ID: 5467709 IUPAC Name: Sodium L-ascorbate Molecular Formula: C₆H₇NaO₆ UNII (Unique Ingredient Identifier): R85B3EXG1N SMILES Notation: C(C(=O)O)C1=CC(=O)O[C@H]2OC@HC@HC1O.Na InChI: InChI=1S/C6H8O6.Na/c7-3-1-5(9)6(10)2-4(3)8/h1-2,4,6,8,10H,(H,7,9)/p-1 Properties of Sodium Ascorbate: Melting point: 220 °C (dec.)(lit.) alpha: 104 º (c=1, H2O 25 ºC) Boiling point: 235 °C Density: 1.66 vapor pressure: 0Pa at 25℃ refractive index: 105.5 ° (C=10, H2O) storage temp.: 2-8°C solubility: H2O: 50 mg/mL form: powder color: white to slightly yellow Odor: odorless PH: 7.48(1 mM solution);7.71(10 mM solution);7.64(100 mM solution);7.62(1000 mM solution) optical activity: [α]20/D +105±2°, c = 5% in H2O Water Solubility: 620 g/L (20 ºC) Merck: 14,830 BRN: 3767246 Stability: Stable. Incompatible with strong oxidizing agents. LogP: -4.2 at 21.9℃ Chemical formula: C6H7NaO6 Molar mass: minute white to yellow crystals Odor: odorless Density: 1.66 g/cm3 Melting point: 218 °C (424 °F; 491 K) (decomposes) Solubility in water:  62 g/100 mL (25 °C) 78 g/100 mL (75 °C) Solubility:  very slightly soluble in alcohol insoluble in chloroform, ether Melting point:220 °C (dec.)(lit.) alpha 104 º (c=1, H2O 25 ºC) Boiling point:235 °C Density 1.66 refractive index 105.5 ° (C=10, H2O) storage temp. Store at RT. solubility H2O: 50 mg/mL Specifications of Sodium Ascorbate: Appearance: White to off-white crystalline powder or granules. Assay (Vitamin C content): Typically ≥ 99% (on a dry weight basis). pH (1% solution): Around 7.0 (neutral). Solubility: Freely soluble in water. Moisture Content: ≤ 5% (depending on the grade and processing method). Heavy Metals: Lead (Pb): ≤ 0.001% Arsenic (As): ≤ 0.0001% Cadmium (Cd): ≤ 0.0001% Mercury (Hg): ≤ 0.0001% Microbial Contamination: Total Plate Count: ≤ 1,000 CFU/g (colony-forming units per gram) Yeast & Mold: ≤ 100 CFU/g E. Coli: Negative Salmonella: Negative Loss on Drying: ≤ 5% (indicates moisture content). Names of Sodium Ascorbate: Regulatory process names: Sodium ascorbate Sodium ascorbate sodium ascorbate IUPAC names: (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one 2,3-didehydro-L-threo-hexono-1,4-lactone sodium enolate; 2,3-Dideshidro-L-treo-hexono-1,4-lactona enolato de sodio 3-oxo-L-gulofuranolactone Ascorbato di Sodio E301 L(+)-Ascorbic acid sodium salt L-Ascorbic acid, monosodium salt sodium (2R)-2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate (non-preferred name) sodium 2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate Sodium Ascorbate Sodium ascorbate sodium ascorbate Sodium ascorbate sodium;2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2H-furan-3-olate Other identifiers: 1017795-34-4 1184919-96-7 129940-98-3 134-03-2 156683-68-0 884311-57-3