OIT (N-OCTYL ISOTHIAZOLINONE)

OIT (OCTYL ISOTHIAZOLINE)

Cas No : 26530-20-1

SYNONYMS: 2,3-Octylisothiazolone; 2-Octyl-4-isothiazolin-3-one;
Octhilinone; 2-Octyl-3(2H)-isothiazolone; 2-n-Octyl-4-isothiazolin-3-one;
Kathon 893; Kathon LM; 2-Octyl-2H-isothiazol-3-one; 2-Octyl-3-isothiazolone;
2-n-Octyl-4-isothiazolin-3-one; Other RN: 122667-23-6, 12673-72-2, 245125-70-6,
249757-59-3, 53028-82-3, 68480-30-8 (hydrochloride); C11H19NOS; oktil
izotiazolinon; OIY; oktilizotiazolinon; oktil izo tiazolinon; n-oktil
izotiazolinon; kathon-893; athon-lm; Acticide 45, acticide epw, acticide epw 1,
acticide ota 20, acticide otp 10, acticide otw, acticide dw, oit, oktil
izotiazolin, oktil, 2-Octyl-2H-isothiazol-3-one, N- OCTYL ISOTHIAZOLINONE,
nipacide oit, cas no : 26530-20-1; 2-Octyl-2H-isothiazol-3-one, biocide,
biyosit. Octhilinone 26530-20-1,2-octylisothiazol-3(2H)-one,2-n-Octyl-4-isothiazolin-3-one,2-Octyl-4-isothiazolin-3-one,2-Octyl-3-isothiazolone,Pancil,2-Octyl-2H-isothiazol-3-one,3(2H)-Isothiazolone, 2-octyl-,2-Octyl-3(2H)-isothiazolone,Kathon 893,Skane 8,Skane M-8,Kathon 893F,Micro-chek skane,Kathon LM,Microbicide M-8,Micro-chek 11,Micro-chek 11D,Kathon SP 70,Kathon LP preservative,Kathon 4200,Pancil-T,Skane M8,2-octyl-1,2-thiazol-3-one,Caswell No. 613C,4-Isothiazolin-3-one, 2-octyl-,UNII-4LFS24GD0V,Vinylzene IT 3000DIDP,Octyl-3(2H)-isothiazolone,RH 893,Octhilinone [ANSI:BSI:ISO],CCRIS 6082,EINECS 247-761-7,2-Octyl-3-isothioazolone,2-Octyl-3 isothiazolinone,Octyl-4-isothiazol-3-one,EPA Pesticide Chemical Code 099901,2-n-Octyl-3-isothiazolone,BRN 1211137,4LFS24GD0V,MLS002415697,CHEBI:81936,2-octyl-1,2-thiazol-3(2H) one,SMR001370885,DSSTox_CID_5805,DSSTox_RID_77928,DSSTox_GSID_25805,W 107168,Kathon,CAS-26530-20-1,C11H19NOS,Pancil T,Skane M 8,ACMC-1CDE4,Vinyzene IT 3000DIDP,SCHEMBL15648,cid_33528,KSC163A4D,SCHEMBL396433,CHEMBL1562104,DTXSID1025805,BDBM66023,HSDB 6713,KS-00000ZYZ,ZINC2012904,Tox21_201459,Tox21_300566,ANW-26014,RH-893,AKOS015897428,LS-1106,ACM25339531,ACM26530201,NCGC00091875-01,NCGC00091875-02,NCGC00091875-03,NCGC00091875-04,NCGC00091875-05,NCGC00254466-01,NCGC00259010-01,AK109069,AS-11894,CC-11727,Octhilinone 10 microg/mL in Acetonitrile,AX8013468,DB-028182,FT-0613248,NS00000270,O0343,O0378,C18752,K-6861,530O201,C-24530,Q2013949,2-Octyl-4-isothiazolin-3-one, PESTANAL(R), analytical standard,OCTYLISOTHIAZOLINONE;Octhilinone;2-Octyl-3(2H)-isothiazolone;2-octyl-2H-isothiazol-3-one
hydrochloride, 2-octil-2H-isotiazol-3-ona (es),
2-Octil-2H-isotiazol-3-ona (OIT) (es),2-octil-2H-isotiazol-3-onă (OIT)
(ro),2-octil-2H-isotiazole-3-ona (pt),2-octil-2H-izotiiazol-3-ona (ro),2-octyl-2H-isothiazol-3-on
(da),2-octyl-2H-isothiazol-3-on (OIT) (da),2-octyl-2H-isothiazol-3-one (OIT)
(mt),2-octyl-2H-isothiazole-3-one (OIT) (fr),2-octyl-2H-isothiazool-3-on
(nl),2-Octyl-2H-isothiazool-3-on (OIT) (nl),2-oktil-2H-izotiazol-3-on
(hr),2-oktil-2H-izotiazol-3-on (hu),2-oktil-2H-izotiazol-3-on (OIT)
(hr),2-oktil-2H-izotiazol-3-onas (lt),2-oktil-2H-izotiazol-3-onas (OIT)
(lt),2-Oktil-2H-izotiazol-3-ons (OIT) (lv),2-oktil-2H-izotiazolons-3
(lv),2-oktyl-2H-isotiazol-3-on (no),2-oktyl-2H-isotiazol-3-on (OIT)
(sv),2-oktyl-2H-izotiazol-3-ón (sk),2-oktyl-2H-izotiazol-3-ón (OIT)
(sk),2-oktylo-2H-izotiazol-3-on (OIT) (pl),2-oktyloizotiazol-3(2H)-on
(pl),2-oktyltetrahydroisothiazol-3-on (cs),2-oktyltetrahydroisothiazol-3-on
(OIT) (cs),2-oktyyli-2H-isotiatsol-3-oni (OIT)
(fi),2-oktyyli-2H-isotiatsoli-3-oni (fi),2-oktüül-2H-isotiasool-3-oon
(et),2-oktüül-2H-isotiasool-3-oon (OIT) (et),2-ottil-2H-isotiazol-3-one
(it),2-ottil-2H-isotiazol-3-one (OIT) (it),2-οκτυλ-2H-ισοθειαζολόνη-3 (OIT)
(el),2-οκτυλο-2H-ισοθειαζολ-3-όνη (el),2-октил-2H-изотиазол-3-он
(bg),2-октил-2H-изотиазол-3-он (OIT) (bg),octhilinon (da),Octhilinon (ISO)
(de),octhilinone (ISO) (cs),octhilinone (ISO);2-octyl-2H-isothiazol-3-one
(fr),octilinon (ISO) (ro),oktilinon (ISO), 4,5-Dichloro-2-octyl-isothiazolone, (hr),oktilinonas
(ISO) (lt),oktilinons (ISO) (lv),oktilinoon (ISO) (et),oktilinón (ISO)
(sk),октилинон (ISO) (bg), DCOIT;C-9211;DCOIT-30;DCOIT-99;DCOIT
97;KATHON287;kathon 930;duracide l;Kathon 287T;Sea-Nine 211, CB4279833,
C11H17Cl2NOS, 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one,
5-Dichloro-2-octyl-3(2H)-isothiazolone2-(4,5-dichlorooctyl)-2,3-dihydro-1,2-thiazol-3-one4,5-dichloro-2-n-octDCOIT-99DCOIT-304,5-Dichloro-2-n-octyl-4-isothiazolin-3-oneKathon,287T4,5-DICHLORO-2-N-OCTYL-3(2H)-ISOTHIAZOLONE4,5-dichloro-2-octyl-3(2h)
isothiazolone4,5-Dichloro-2-octyl-isothiazolonekathon930Dichloro-2-n-octyl-3(2H)-isothiazoloneduracidel4,5-dichloro-2n-octyl-3-isothiazolone4,5-Dichloro-N-octyl-3(2H)-isothiazoloneDCOIT4,5-dichloro-2-octyl-2H-isothiazol-3-one4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one4,5-Dichloro-N-octyl–4-isothiazolin-3-one4,5-Dichloro-N-octyl–4-isothiazolin-3-one4,5-Dichloro-2-Octyl-3-Isothiazolone4,5-dichloro-2n-octyl-3-isothiazolone(DCOIT)4,5-DICHLORO-2-N-OCTYL-ISOTHIAZOLINONEKATHON2874,5-Dichlor-2-octyl-2H-isothiazol-3-on4,5-dichloro-2-n-octyl-4-isothiazolone-3-one4,5-dichloro-2-octyl-3(2h)-isothiazolonkathon
925(4,5-dichloro-2-n-octyl-4-isothiazolin-3-one)4,5-Dichloro-N-octyl-4-isothiazol-3-one4,5-Dichloro-2-octylisothiazol-3(2H)-oneC-9211Sea-Nine
2114,5-DICHLORO-2-N-OCTYLISOTHIAZOL-3-ONE4.5-DICHLORO-2H-OCTYL-3(2H)-ISOTHIAZOLONEAnti-foulant
C-9211mCaswell no. 314bEinecs 264-843-8Epa pesticide chemical code 1281014,5-dichloro-2-n-octyl-4-isothiazolin-3-one
(DCOIT)3(2H)-Isothiazolone, 4,5-dichloro-2-octyl-DCOIT
974,5-Dichloro-2-octyl-isothiazoloneDCOIT4,5-dichloro-2-octyl-3H-isothiazole
1-oxide4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one>64359-81-5C11H17Cl2NOS, 3(2H)-ISOTHIAZOLONE,
2-OCTYL 4-ISOTHIAZOLIN-3-ONE, 2-OCTYL-,KATHON 4200,KATHON 893,KATHON LM,KATHON
LP PRESERVATIVE,KATHON SP 70,MICRO-CHEK 11,MICRO-CHEK 11D,MICRO-CHEK
SKANE,2-N-OCTYL-3-ISOTHIAZOLONE,2-N-OCTYL-4-ISOTHIAZOLIN-3-ONE,2-N-OCTYLISOTHIAZOLIN-3-NE,OCTHILINONE,2-OCTYL-3(2H)ISOTHIAZOLONE,2-OCTYL-3-ISOTHIAZOLINONE,2-OCTYL-3-ISOTHIAZOLONE,2-OCTYL-4-ISOTHIAZOLIN-3-ONE,2-OCTYL-4-ISOTHIAZOLINONE,PANCIL,PANCIL
T,PANCIL-T,RH 893,SKANE 8,SKANE HQ,SKANE M 8,SKANE M8,VINYZENE IT 3000DIDP Isothiazole
Thiazole thiazol-3-one Isothiazolinones 2-Methyl-4-isothiazolin-3-one
hydrochloride decene 5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride
4,5-Dichloro-2-octyl-isothiazolone OCTYL GLUCOSIDE CAPRYLYL PYRROLIDONE
Octyldodecyldimethylammonium chloride Kathon Dichloroacetonitrile 5-Chloro-2-methyl-3(2H)-isothiazolone
with 2-methyl-3(2H)-isothiazolone Methylisothiazolinone
2-Octyl-2H-isothiazol-3-one 2′,4′-Dichloroacetophenone,
2-oktil-2H-izotiazol-3-onas (OIT) (lt),2-Oktil-2H-izotiazol-3-ons (OIT)
(lv),2-oktil-2H-izotiazolons-3 (lv),2-oktyl-2H-isotiazol-3-on
(no),2-oktyl-2H-isotiazol-3-on (OIT) (sv),2-oktyl-2H-izotiazol-3-ón
(sk),2-oktyl-2H-izotiazol-3-ón (OIT) (sk),2-oktylo-2H-izotiazol-3-on (OIT)(pl),2-oktyloizotiazol-3(2H)-on(pl),2-oktyltetrahydroisothiazol-3-on(cs),2
oktyltetrahydroisothiazol-3-on (OIT) (cs),2-oktyyli-2H-isotiatsol-3-oni (OIT)
(fi),2-oktyyli-2H-isotiatsoli-3-oni (fi),2-oktüül-2H-isotiasool-3-oon (et) OIT,
KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT,
Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL
ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin

OIT (OCTYL ISOTHIAZOLINE)

Isothiazolinones containing sulfur atom
(S), nitrogen (N), oxygen (O) at 3 position and hydrogen (H) can find
application for making broad-spectrum biocides and preservatives such as
antiseptic agents, bactericides, slimicides, and fungicides. The biggest
application is in paint industry especially marine antifouling agent. They are
also used in adhesives, cutting oils, water systems, cosmetics, household goods
and wound protectant for pruning cuts. They are also used as pulp and wood
impregnating agents as well as in leather, fur and polymer process. It is known
to cause allergy and chemical burn if high concentration is used in personal
care products and cosmetics. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Octylisothiazolinone is used almost
exclusively as a preservative in latex paints, but a small proportion is also
used as a preservative in the leather and fur industries. Isothiazolines are
also used as slime control agents in the pulp industry and as wood impregnating
agents. Low concentrations, mostly <<0.01 %, of isothiazolines are present in a large number of products, which means that the volumes reported are averages with a wide interval. Concentrations are often given as maximum values, which compounds the uncertainty regarding these volumes. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) 2-Octyl-2H-isothiazol-3-one Chemical Properties,Uses,Production Description This isothiazolione, octylisothiazolinone, is contained in relatively fewer products than other isothiazolinones. Chemical Properties Yellow solid or clear dark amber liquid. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Chemical Properties OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Light Yellow Oil Uses Fungicide. Antimicrobial agent Uses Fungicide. Biocide in cooling-tower water, paints, cutting oils, cosmetics and shampoo; for leather preservation. Uses 2-n-Octyl-4-isothiazolin-3-one is a mildeweide; bactericide; fungicide; biocide in cooling-tower water; in paints, cutting oils, cosmetics, and shampoos; leather preservation; wound protectant for pruning cuts. Definition ChEBI: A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It i no longer approved for use within the European Union. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), General Description Clear dark amber liquid. Used as a fungicide. Air & Water Reactions Insoluble in water. Reactivity Profile 2-Octyl-2H-isothiazol-3-one reacts as an isothiocyanate. Isothiocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Fire Hazard 2-Octyl-2H-isothiazol-3-one is probably combustible. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Contact allergens This isothiazolinone, contained in relatively few products compared to other isothiazolinones, is used in cleaning and polishing agents, latex paints, stains, adhesives, wood and leather preservatives, metalworking fluids (cutting oils), and plastic manufacture. Safety Profile Moderately toxic by ingestion and skin contact. A skin and severe eye irritant. A rmldewcide. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also KETONES. Potential Exposure Isothiazolone/isothiocyanate/heteroaramatic fungicide and microbiocide used on textiles, in metalworking fluids, and some water thinned paints. Its use as a fungicide on cotton was canceled in the United States and the tolerances were revoked in 1998. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Shipping UN2922 Corrosive liquids, toxic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 6.1-Poisonous materials. Incompatibilities Oxidizers. Contact with hydrogen peroxide may form explosive material. Isothiocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Ketones behave a weak acid. Forms water soluble alkali metal salts. Ketones are reactive with many acids and bases liberating heat and flammable gases. The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable hydrogen gas and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, nitric acid, and perchloric acid. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Waste Disposal Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations. 2-Octyl-2H-isothiazol-3-one Preparation Products And Raw materials 3.2Experimental Properties HelpNew Window 3.2.1Physical Description HelpNew Window 2-octyl-3-isothiazolone is a clear dark amber liquid. Used as a fungicide. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), CAMEO Chemicals 3.2.2Color/Form HelpNew Window Liquid American Conference of Governmental Industrial Hygienists. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH 2012, p. 1256 Hazardous Substances Data Bank (HSDB) Light, golden yellow, clear liquid OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010) Hazardous Substances Data Bank (HSDB) 3.2.3Odor HelpNew Window Very weak, sharp smell OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Hazardous Substances Data Bank (HSDB) 3.2.4Boiling Point HelpNew Window 248 °F at 0.01 mm Hg (NTP, 1992) National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) CAMEO Chemicals 342 °C at 101.325 kPa (est) ECHA; Search for Chemicals. Octhilinone (36530-20-1) Registered Substances Dossier. European Chemical Agency. Available from, as of July 9, 2018: http://echa.europa.eu/ Hazardous Substances Data Bank (HSDB) 3.2.5Melting Point HelpNew Window 15 °C at 101.325 kPa ECHA; Search for Chemicals. Octhilinone (36530-20-1) Registered Substances Dossier. European Chemical Agency. Available from, as of July 9, 2018: http://echa.europa.eu/ OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Hazardous Substances Data Bank (HSDB) 3.2.6Flash Point HelpNew Window greater than 200 °F (NTP, 1992) OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. CAMEO Chemicals 3.2.7Solubility HelpNew Window less than 1 mg/mL at 66° F (NTP, 1992) National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina. CAMEO Chemicals 0.00 M OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) TOMLIN,C (1994) EPA DSSTox In distilled water, 500 mg/L at 25 °C MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010) Hazardous Substances Data Bank (HSDB) In toluene >800, ethyl acetate >900,
hexane 64 (all in g/L at 25 °C)

MacBean C, ed; e-Pesticide Manual. 15th
ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone
(26530-20-1) (2008-2010)

Hazardous
Substances Data Bank (HSDB) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon,
isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL
İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin

OIT,
KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT,
Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL
ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin

3.2.8Density HelpNew Window

1.04 at 60.3 °F (NTP, 1992)

National Toxicology Program, Institute of
Environmental Health Sciences, National Institutes of Health (NTP). 1992.
National Toxicology Program Chemical Repository Database. Research Triangle
Park, North Carolina.

CAMEO Chemicals

1.03

USEPA/OPP; Pesticide Chemical Search. RED.
Octhilinone. (26530-20-1). Sept 2007. EPA 739-R-07-008. Washington, DC:
Environmental Protection Agency, Office of Pesticide Programs. Available from,
as of July 9, 2018: http://iaspub.epa.gov/apex/pesticides/f?p=chemicalsearch:1

Hazardous Substances Data Bank (HSDB)

3.2.9Vapor Pressure HelpNew Window

2.98 mm Hg at 77 °F (NTP, 1992)

CAMEO Chemicals

3.68e-05 mmHg

EPA DSSTox

3.68X10-5 mm Hg (4.9 mPa) at 25 °C

MacBean C, ed; e-Pesticide Manual. 15th
ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone
(26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

3.2.10LogP HelpNew
Window

2.45 (LogP)

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT
(OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),

TOMLIN,C (1994)

EPA DSSTox

log Kow = 2.45 at 24 °C

MacBean C, ed; e-Pesticide Manual. 15th
ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone
(26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

3.2.11Stability/Shelf Life HelpNew Window

Stable
under recommended storage conditions. OIT, KATLON, KATHON IZOTIYAZOLINON,
isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL
ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL
İZOTİYAZOLİN, octil izatiyazolin

Sigma-Aldrich; Safety Data Sheet for
2-Octyl-4-isothiazolin-3-one. Product Number: 46078, Version 5.2 (Revision Date
03/13/2015). Available from, as of June 15, 2018:
http://www.sigmaaldrich.com/safety-center.html

Hazardous Substances Data Bank (HSDB)

3.2.12Decomposition HelpNew Window

When heated to decomposition it emits very
toxic fumes of /sulfur oxides and nitrogen oxides/.

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT
(OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),
OIT (OCTYL ISOTHIAZOLINE),Lewis, R.J. Sr. (ed) Sax’s Dangerous Properties of
Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc.
Hoboken, NJ. 2004., p. 2769

Hazardous Substances Data Bank (HSDB)

3.2.13Viscosity HelpNew Window

48.04 sq mm.s at 20 °C; 17.94 sq mm.s at
30 °C

3.2.14pH HelpNew
Window

pH = 3.4

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT
(OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),

Hazardous Substances Data Bank (HSDB)

3.2.15Kovats Retention Index HelpNew Window

Semi-standard non-polar 1822.6, 1849

NIST Mass Spectrometry Data Center

3.2.16Other Experimental Properties HelpNew Window

BP: 120 °C at 0.01 mm Hg

MacBean C, ed; e-Pesticide Manual. 15th
ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone
(26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

Relative density: 1.04 at 15 °C; log Pow:
2.61 at 25 °C, pH 7

ECHA; Search for Chemicals. Octhilinone
(36530-20-1) Registered Substances Dossier. European Chemical Agency. Available
from, as of July 9, 2018: http://echa.europa.eu/

Hazardous Substances Data Bank (HSDB)

log Kow = 3.42

Hazardous Substances Data Bank (HSDB)

Stable to light

MacBean C, ed; e-Pesticide Manual. 15th
ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone
(26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

Henry’s
Law constant = 2.07X10-8 atm-cu m/mol at 25 °C (est) OIT, KATLON, KATHON
IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N-
OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL
İZOTİYAZOLİN, octil izatiyazolin

US EPA; Estimation Program Interface (EPI)
Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018:
http://www2.epa.gov/tsca-screening-tools

Hydroxyl radical reaction rate constant =
2.94X10-11 cu cm/molec-sec at 25 °C (est)

US EPA; Estimation Program Interface (EPI)
Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018:
http://www2.epa.gov/tsca-screening-tools

Hazardous Substances Data Bank (HSDB)

Ozone reaction rate constant = 1.75X10-18
cu cm/molec-sec at 25 °C (est)

US EPA; Estimation Program Interface (EPI)
Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018:
http://www2.epa.gov/tsca-screening-tools

Hazardous Substances Data Bank (HSDB)

Chemical Name:
2-n-octyl-4-isothiazolin-3-one; 2-Octyl-2H-isothiazol-3-one;
Octylisothiazolinone; Kathon 893

CAS NO.: 26530-20-1

Molecular formula: C11H19NOS

Molecular weight: 213.34

Technical index

Appearance

Pale brown liquid

Content of active substance %

≥98%

PH value

4.0-7.0

Density(25℃) g/cm3

1.00-1.05

COA Download: Here

MSDS: Contact us for MSDS file.

Applications

It is mainly used as biocides and
preservatives for coatings, paints, resins emulsions, oil water emulsions,
photo-chemicals, in Paint, inks, lubricant, shoes cream, leather chemical, wood
product and cultural relic protection etc.

Features:

1. Broad-spectrum sterilization,with good
inhibiting capacity towards bacteria, mould, Fungus and ferment.

2. Lox toxicity,long lasting effect: Free
of formaldehyde，No smell.

3. Strong Bactericidal power:with strong
capability of killing moulds, effect is obvious than the traditional
Fungicide,is a kind of proper replacement of traditional film Fungicide.

4. No impact to environment. The products
can be degrade naturally to Non-toxic substance,will not cause pollution to
environment.

Safety/Operation/Toxicity：

Avoid any contact with the skin. Wear
protective clothes, goggles, and rubber gloves in operation. Once touch, will
be sensitive to skin.Irritating to the skin and eyes.

Remarks:

When the final products content is lower
than 1.79%, don’t need special tagging,once above 1.79% ,please consult with
factory technique lab.

Package:25Kgs,200 Kgs drum

Storage: With a shelf time of one year
when stored at room temperature in a dark, air-tight, and moisture-proof place.

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT
(OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),
OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL
ISOTHIAZOLINE),

Transport Mode:

Multipletransportation
methods can be selected, Sea Transport, Air Transport, Express Transport and
Railway Transport. The transport method will be done according to customers’
request. Our priciple is to delivery the goods reached to customers with
shortest time and ecomomic transport mode, safe and fast. OIT, KATLON, KATHON
IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N-
OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL
İZOTİYAZOLİN, octil izatiyazolin

Octylisothiazolinone
is also used almost exclusively as a preservative in latex paints, but a small
proportion is also used as a preservative in the leather and fur industries.
Isothiazolines are also used as slime control agents in the pulp industry and
as wood impregnating agents. Low concentrations, mostly <<0.01 %, of isothiazolines are present in a large number of products, which means that the volumes reported are averages with a wide interval. Concentrations are often given as maximum values, which compounds the uncertainty regarding these volumes. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Isothiazolinones containing sulfur atom (S), nitrogen (N), oxygen (O) at 3 position and hydrogen (H) can find application for making broad-spectrum biocides and preservatives such as antiseptic agents, bactericides, slimicides, and fungicides. The biggest application is in paint industry especially marine antifouling agent. They are also used in adhesives, cutting oils, water systems, cosmetics, household goods and wound protectant for pruning cuts. They are also used as pulp and wood impregnating agents as well as in leather, fur and polymer process. It is known to cause allergy and chemical burn if high concentration is used in personal care products and cosmetics. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Common biocides ( antiseptic agents, preservatives, bactericides, slimicides, fungicides) in cosmetics are parabens, isothiazolones, formaldehyde and formaldehyde releasing substances such as quaternium 15, diazolidinyl urea. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin GENERAL DESCRIPTION OF ANTISEPTIC AGENT: Antiseptic agent is a substance which kills or inhibits the growth of disease-causing bacteria and other microorganisms. It is essentially nontoxic to to be applied to the skin or mucous membranes. (Disinfectant including cresol, bleaching powder, and phenol is in general toxic to cells of the body). Common antiseptic agents are Benzalkonium Chloride, Cetrimide, Chlorhexidine, Hexachlorophene, Iodine Compounds, Mercury Compounds (Thimerosol), Alcohol and Hydrogen Peroxide, Hexamine Hippurate, Triclosan, Cetylpyridinium Chloride, And Dequalinium. Other substances which can be used for antiseptic purpose include Boric acid and volatile oils such as Methyl Salicylate. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Hexachlorophene and Benzalkonium Chloride are used primarily in hand or face washes. Benzalkonium Chloride must not be applied to areas which have not been fully rinsed as it is inactivated by organic compounds. Benzalkonium application many include disinfecting instruments and preservativing drugs in low concentration form. Iodine compounds have the widest spectrum of antiinfectives against bacteria, fungi, spores, protozoa, viruses, and yeasts. Aqueous iodine are less effective than alcoholic solutions, but alcoholic component is drying and irritating to abraided skin. Povidone iodine is convenient to use as it is less irritating, but not as effective. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Chlorhexidine is used as a safe antiseptic or disinfectant to apply to prevent body infection and in oral rinses for treating sore gums and mouth ulcers and preventing plaque on teeth. It is used in the form of acetate, gluconate or hydrochloride, either alone or in combination with others such as cetrimide. Cetrimide is an antiseptic agent with detergent properties. It has the wide spectrum of antiinfectives against bacteria and fungi. It is used as an ingredient of shampoos for treating seborrhoea and psoriasis. A very dilute solution can be applied topically for the relief of sore gums. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin Hippuric Acid, an amino acid glycine, is excreted from the body and is used in urinary system drugs. Hexamine hippurates is helpful for preventing and treating infections of the urinary system; it acts by being transformed to formaldehyde. Triclosan is a very popular antibacterial agent. It is used in hospitals for cleansing and disinfecting the skin of patients and surgeons. It is used in cosmetics, household goods and personal care products. It is also used in plastics and textiles for antibacterial activity purpose. Cetylpyridinium chloride is used in oral rinses for cleaning mouth and treating minor throat or mouth infections and teething problems. Dequalinium chloride is antiinfectives against bacteria and fungi. It is used in treating bacterial or fungal infections of mouth and throat. İzotiyazolinon (izotiyazolon ), izotiyazol ile ilgili heterosilik bir kimyasal bileşiktir . Diğer birçok basit heterosiklete kıyasla, keşfi oldukça yenidir ve raporlar ilk olarak 1960'larda ortaya çıkmıştır. Bileşiğin kendisinin herhangi bir uygulaması yoktur, ancak türevleri yaygın olarak biyositler olarak kullanılmaktadır . Sentez Çeşitli sentetik yollar bildirilmiştir. İzotiyazolinonlar tipik olarak endüstriyel ölçekte 3-sülfanilpropanamid türevlerinin halka kapatılmasıyla hazırlanır. Bunlar da 3-merkaptopropionik asit yoluyla akrilik asitten üretilir . İzotiyazolinon sentezi Halka kapatma, tiyol grubunun, nitrojen merkezi tarafından nükleofilik saldırıya maruz kalan reaktif bir türe dönüştürülmesini içerir . Bu tipik olarak klorinasyonu [1] veya 3-sülfanilpropanamidin karşılık gelen disülfür türlerine oksidasyonunu içerir . Bu reaksiyon koşulları, aynı zamanda , istenen ürünü vermek üzere ara izotiyazolidin halkasını da oksitlemektedir . Uygulamalar İzotiazolinon olan antimikrobik maddeler kontrol için kullanılan bakteriler , mantarlar ve yosunların içinde soğutma suyu sistemleri , yakıt depolama tankları , kağıt hamuru ve kağıt fabrikası su sistemleri, petrol çıkarma sistemleri, ahşap koruma ve kirlenme önleyici maddeler. Şampuanlar ve diğer saç bakım ürünleri gibi kişisel bakım ürünlerinde ve belirli boya formülasyonlarında sıklıkla kullanılırlar . Genellikle, MIT ve CMIT kombinasyonları ( Kathon CG olarak bilinir)) veya MIT ve BIT kullanılır. Örnek bileşikler Metilizotiyazolinon (MIT, MI) Klorometilizotiyazolinon (CMIT, CMI, MCI) Benzisothiazolinone (BIT) Octylisothiazolinone (OIT, OI) Dichlorooctylisothiazolinone (DCOIT, DCOI) Butylbenzisothiazolinone (BBIT) Biyolojik çıkarımlar İzotiyazolinonların mikroorganizmaları kontrol etme veya öldürme işlevleriyle birlikte istenmeyen etkileri de vardır: OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin, Yüksek su toksisitesine sahiptirler ve bazı türevleri doğrudan temas veya hava yoluyla aşırı duyarlılığa neden olabilir . 3 konumunda kükürt atomu (S), nitrojen (N), oksijen (O) ve hidrojen (H) içeren izotiyazolinonlar, antiseptik maddeler, bakterisitler, ince öldürücüler ve mantar öldürücüler gibi geniş spektrumlu biyositler ve koruyucular yapmak için uygulama bulabilir. En büyük uygulama boya endüstrisinde, özellikle denizcilikte zehirli boyadır. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin, Ayrıca yapıştırıcılarda, kesme yağlarında, su sistemlerinde, kozmetik ürünlerinde, ev eşyalarında ve budama kesikleri için yara koruyucularda kullanılırlar. Deri, kürk ve polimer işlemlerinin yanı sıra hamur ve ahşap emprenye maddeleri olarak da kullanılırlar. Kişisel bakım ürünlerinde ve kozmetikte yüksek konsantrasyon kullanılması halinde alerji ve kimyasal yanıklara neden olduğu bilinmektedir. Octylisothiazolinone, lateks boyalarda neredeyse sadece bir koruyucu olarak kullanılır, ancak küçük bir kısmı da deri ve kürk endüstrisinde koruyucu olarak kullanılır. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTİL İZOTİYAZOLİNONE, OCTYL ISOTHIAZOLINE, OKTİL İZOTİYAZOLİN, octil izatiyazolin, İzotiyazolinler ayrıca hamur endüstrisinde ve ahşap emprenye maddeleri olarak balçık kontrol maddeleri olarak kullanılır. İzotiyazolinlerin düşük konsantrasyonları, çoğunlukla << 0.01%, çok sayıda üründe mevcuttur, bu da rapor edilen hacimlerin geniş aralıklı ortalamalar olduğu anlamına gelir. Konsantrasyonlar genellikle maksimum değerler olarak verilir, bu da bu hacimlerle ilgili belirsizliği birleştirir. 2-Octyl-2H-isothiazol-3-one Kimyasal Özellikleri, Kullanım Alanları, Üretimi Açıklama Bu izotiyazolon, oktilizotiyazolinon, diğer izotiyazolinonlara kıyasla nispeten daha az üründe bulunur. Kimyasal özellikler Sarı katı veya berrak koyu kehribar sıvı. Kimyasal özellikler Açık Sarı Yağ Kullanımlar Mantar ilacı. Antimikrobiyal ajan Kullanımlar Mantar ilacı. Soğutma kulesi suyunda, boyalarda, kesme yağlarında, kozmetiklerde ve şampuanda biyosit; deri koruma için. Kullanımlar 2-n-Oktil-4-izotiyazolin-3-on bir; bakterisit; mantar ilacı; soğutma kulesi suyundaki biyosit; boyalarda, kesme yağlarında, kozmetiklerde ve şampuanlarda; deri koruma; budama kesimleri için yara koruyucu. Octylisothiazolinone de hemen hemen sadece lateks boyalarda koruyucu olarak kullanılır, ancak küçük bir kısmı da deri ve kürk endüstrisinde koruyucu olarak kullanılır. İzotiyazolinler ayrıca hamur endüstrisinde ve ahşap emprenye maddeleri olarak balçık kontrol maddeleri olarak kullanılır. İzotiyazolinlerin düşük konsantrasyonları, çoğunlukla << 0.01%, çok sayıda üründe mevcuttur, bu da rapor edilen hacimlerin geniş aralıklı ortalamalar olduğu anlamına gelir. Konsantrasyonlar genellikle maksimum değerler olarak verilir, bu da bu hacimlerle ilgili belirsizliği birleştirir. kükürt atomu (S), nitrojen (N), oksijen (O) ve hidrojen (H) içeren izotiyazolinonlar, antiseptik maddeler, bakterisitler, ince öldürücüler ve mantar öldürücüler gibi geniş spektrumlu biyositler ve koruyucular yapmak için uygulama bulabilir . En büyük uygulama boya endüstrisinde, özellikle denizcilikte zehirli boyadır. Ayrıca yapıştırıcılarda, kesme yağlarında, su sistemlerinde, kozmetik ürünlerinde, ev eşyalarında ve budama kesikleri için yara koruyucularda kullanılırlar. Deri, kürk ve polimer işlemlerinin yanı sıra hamur ve ahşap emprenye maddeleri olarak da kullanılırlar. Kişisel bakım ürünlerinde ve kozmetikte yüksek konsantrasyon kullanılması halinde alerji ve kimyasal yanıklara neden olduğu bilinmektedir. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), Kozmetiklerde yaygın olarak kullanılan biyositler (antiseptik maddeler, koruyucular, bakterisitler, sümüksüitler, mantar öldürücüler) parabenler, izotiyazolonlar, formaldehit ve kuaterniyum 15, diazolidinil üre gibi formaldehit salan maddelerdir. ANTİSEPTİK AJANIN GENEL AÇIKLAMASI : Antiseptik ajan, hastalığa neden olan bakteri ve diğer mikroorganizmaları öldüren veya büyümesini engelleyen bir maddedir. Deriye veya mukoza zarlarına uygulanması esasen toksik değildir. (Kresol, ağartma tozu ve fenol içeren dezenfektan genel olarak vücut hücreleri için toksiktir). Yaygın antiseptik ajanlar, Benzalkonyum Klorür, Setrimid, Klorheksidin, Heksaklorofen, İyot Bileşikleri, Cıva Bileşikleri (Timerosol), Alkol ve Hidrojen Peroksit, Heksamin Hippurat, Triklosan, Setilpiridinyum Klorür ve Dekualinyumdur. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)Antiseptik amaçla kullanılabilen diğer maddeler arasında Borik asit ve Metil Salisilat gibi uçucu yağlar bulunur. Hekzaklorofen ve Benzalkonyum Klorür esas olarak el veya yüz yıkamada kullanılır. Benzalkonyum Klorür, organik bileşikler tarafından inaktive edildiğinden tam olarak durulanmamış alanlara uygulanmamalıdır. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)Benzalkonyum uygulamasının birçoğu, dezenfekte edici aletler ve düşük konsantrasyon formundaki koruyucu ilaçları içerir. İyot bileşikleri, bakterilere, mantarlara, sporlara, protozoa, virüslere ve mayalara karşı en geniş anti-infektif spektrumuna sahiptir. Sulu iyot, alkollü solüsyonlardan daha az etkilidir, ancak alkollü bileşen, tahriş olmuş cildi kurutur ve tahriş eder. Povidon iyot, daha az tahriş edici olduğu, ancak aynı derecede etkili olmadığı için kullanımı uygundur. Klorheksidin, vücut enfeksiyonunu önlemek için güvenli bir antiseptik veya dezenfektan olarak ve diş etleri ve ağız ülserlerini tedavi etmek ve dişlerde plak oluşumunu önlemek için ağız çalkalamalarında kullanılır. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Tek başına veya setrimid gibi diğerleri ile kombinasyon halinde asetat, glukonat veya hidroklorür formunda kullanılır. Setrimid, deterjan özelliklerine sahip antiseptik bir ajandır. Bakteri ve mantarlara karşı geniş bir anti-infektif yelpazesine sahiptir. Sebore ve sedef hastalığını tedavi etmek için şampuanların bir bileşeni olarak kullanılır. Ağrıyan diş etlerinin rahatlaması için topikal olarak çok seyreltik bir çözelti uygulanabilir. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Bir amino asit glisin olan Hippurik Asit vücuttan atılır ve üriner sistem ilaçlarında kullanılır. Heksamin hippuratlar, üriner sistem enfeksiyonlarını önlemek ve tedavi etmek için faydalıdır; formaldehite dönüştürülerek hareket eder. Triklosan çok popüler bir antibakteriyel ajandır. Hastanelerde hasta ve cerrahların cildinin temizlenmesi ve dezenfekte edilmesinde kullanılır. Kozmetikte, ev eşyalarında ve kişisel bakım ürünlerinde kullanılmaktadır. Plastiklerde ve tekstilde antibakteriyel aktivite amacıyla da kullanılmaktadır. Cetylpyridinium chloride, ağız temizliğinde ve küçük boğaz veya ağız enfeksiyonlarını ve diş çıkarma problemlerini tedavi etmek için ağız durulamalarında kullanılır. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Dequalinium klorür, bakteri ve mantarlara karşı anti-infektiftir. Ağız ve boğazda oluşan bakteriyel veya fungal enfeksiyonların tedavisinde kullanılır. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Tanım ChEBI: 1,2-tiyazol-3-on olan ve nitrojen üzerinde bir oktil grubu ile ikame edilen (pozisyon 2) 1,2-tiyazol sınıfının bir üyesi. Mantar ilacı ve antibakteriyel bir ajan olup meyve ağaçlarında pamukçuk ve diğer mantar ve bakteri hastalıklarının tedavisinde kullanılır. Artık Avrupa Birliği içinde kullanım için onaylanmadı. Genel açıklama Berrak koyu kehribar sıvı. Mantar ilacı olarak kullanılır. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Hava ve Su Reaksiyonları Suda çözünmez. Reaktivite Profili 2-Octyl-2H-isothiazol-3-one, bir izotiyosiyanat olarak reaksiyona girer. İzotiyosiyanatlar, toksik gazları açığa çıkarmak için ekzotermik reaksiyona girerek birçok bileşik sınıfıyla uyumsuzdur. Aminlerle, aldehitlerle, alkollerle, alkali metallerle, ketonlarla, merkaptanlarla, güçlü oksitleyicilerle, hidrürlerle, fenollerle ve peroksitlerle reaksiyonlar şiddetli ısı salınımına neden olabilir. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE) Yangın tehlikesi 2-Octyl-2H-isothiazol-3-one muhtemelen yanıcıdır.

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