PENTYLENE GLYCOL
PENTYLENE GLYCOL
Pentylene glycol is a specific raw material used by manufacturers of green cosmetic products.
Pentylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
Pentylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.
CAS Number: 5343-92-0
EC Number: 226-285-3
Molecular Formula (Pentylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol
Synonyms: 1,2-Pentanediol, Pentane-1,2-diol, 1,2-Dihydroxypentane, 5343-92-0, Pylethylene Glycol, glycol, Glycol, Green Protector, 1,2-Dihydroxypentane, MFCD00010736, 1,a2-aPentanediol, EINECS 226-285-3, BRN 1719151, AI3-03317, NSC 513, 108340-61-0, ACMC-20mbh5, ACMC-1AXDB, EC 226-285-3, 1,2-Pentanediol, 96%, SCHEMBL62155, 3-01-00-02191 (Beilstein Handbook Reference), 1,2-Pentanediol, (2R)-, NSC513, WCVRQHFDJLLWFE-UHFFFAOYSA-, DTXSID10863522, NSC-513, AKOS009156977, AS-40006, SY032914, CS-0017222, FT-0606477, FT-0690841, P1178, 3-(2-NITRO-PHENYL)-ISOXAZOL-5-YLAMINE, 98484-EP2372017A1, A829586, Q3374899
Pentylene glycol is a synthetic compound that belongs to the chemical group called 1,2 glycol.
Pentylene glycol is a transparent liquid, slightly viscous, colorless, odorless and soluble in water as well as oil.
Pentylene glycol is naturally derived from sugar cane.
Pentylene glycol is used in many cosmetic products.
Pentylene glycol is also referred to by the names 1,2- dihydroxypentane, 1,2-pentanediol, and pentane-1,2-diol.
Pentylene glycol is a natural polyhydric alcohol and therefore has the ability to bind water.
This property can be used to moisturize the skin.
Skin is better hydrated, looks significantly brighter and feels better.
At the same time, Pentylene glycol naturally helps inhibit the growth of microorganisms on the skin and can therefore be used as an alternative preservative.
Pentylene glycol is soluble in water, acts as an extractant and solvent, is biodegradable, can be used in the pH range of 3-10, and is colorless and odorless.
Pentylene glycol is made from natural sugar cane bagasse and is therefore ideal for natural cosmetics.
Pentylene glycol is a specific raw material used by manufacturers of green cosmetic products.
The most important feature of this preservative is that Pentylene glycol is obtained from agricultural products. For example, corn and sugar cane.
Pentylene glycol is also commonly called pylene glycol.
Pentylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
There are two alcohol groups attached to the 1st and 2nd carbon.
Pentylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.
Pentylene glycol is also obtained naturally from sugar cane.
Pentylene glycol is also fat-soluble and used in many cosmetic products.
Pentylene glycol is a natural diol derived from sugar cane bagasse’s remaining waste, but a cheap synthetic analog also available in the market.
This multifunctional ingredient is a colorless, odorless, slightly viscous liquid that serves as a moisturizer, solubilizer, preservative, emulsion stabilizer, etc.
Pentylene glycol is a well-known moisturizer due to the humectant properties of the molecule, proven scientifically by in-vivo studies.
Also, Pentylene glycol is an excellent solubilizer, as Pentylene glycol helps to solubilize many challenging ingredients, including fragrances.
Pentylene glycol can also increase the clarity of translucent formulations like aqueous gels and toners.
Pentylene glycol protects products from harmful bacteria and improves shelf-life, working synergistically with many preservatives, boosting their efficacy and thus helping to reduce their dose.
In addition, Pentane-1,2-diol stabilizes formulations, especially oil-in-water emulsions (as a co-emulsifier with an HLB value of 8.4), which helps reduce the particle size of emulsions, thus providing less coalescence and better stability.
This diol enhances the bioavailability of other ingredients (proven by ex-vivo study), boosting the activity of both lipophilic and hydrophilic actives.
Furthermore, Pentylene glycol improves pigment distribution, makes whiter and shinier emulsions, promotes penetration into the skin, and improves the efficiency of cooling agents.
Incorporated in sun care applications, Pentylene glycol enhances water resistance and the entire safety of the formula used even in SPF 50+ products.
Pentylene glycol also can control the viscosity and texture of the final product.
In skin and hair care products and decorative cosmetics, Pentylene glycol concentration can reach up to 5%.
Pentylene glycol is used in formulations as an emulsion stabilizer, solvent and a broad spectrum antimicrobial.
Pentylene glycol also helps moisturize and has a light, elegant feel to it.
Pentylene glycol will leave the skin soft and smooth.
Pentylene glycol can help to solubilize and stabilize lipophilic ingredients in aqueous solutions.
Pentylene glycol shows a broad spectrum antimicrobial activity against yeasts, moulds, and bacteria.
Pentylene glycol disturbs the integrity of microbial cell membranes, a mechanism of action that is unlikely to be affected by resistance.
Being a non-ionic ingredient, the anti-microbial effect of Pentylene glycol is largely pH-independent.
Pentylene glycol can act as a standalone antimicrobial protection agent.
In addition, Pentylene glycol can be easily combined with other classical or non-classical antimicrobial agents, to boost their preservation effects.
Pentylene glycol a synthetic, low molecular weight solvent and skin-conditioning agent.
Pentylene glycol is commonly used as a skin conditioning agent, due to Pentylene glycol (1,2 pentanediol)’s ability to help the skin attract and retain moisture.
As such, Pentylene glycol falls into a category of skin care ingredients called humectants.
Pentylene glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative.
Pentylene glycol is both water and oil-soluble and Pentylene glycol can have moisture-binding and Pentylene glycol can have antimicrobial properties.
Pentylene glycol also has some anti microbial properties, which can make Pentylene glycol a valuable addition to products that are susceptible to contamination of microorganisms.
Pentylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetic industry.
Pentylene glycol is used in sunscreens.
Pentylene glycol is a skin moisturizer.
Pentylene glycol preserves moisture in the skin, helps to preserve elasticity and moisture of the skin.
Pethylene glycol has an antimicrobial effect.
Pethylene glycol Lipid and dissolved lipophilic actives can be used in penetration enhancing creams and lotions.
Pethylene glycol Hydrogenated phosphotidylcholine is a high viscosity base composed of protected lipids and glycerol.
Pentylene glycol is an antimicrobial, chemically produced emulsifier.
Pentilen Glycol has been included in the German Pharmaceutical Codex since 2009.
However, Pentylene glycol is not only approved in Germany, but Pentylene glycol is also approved as a cosmetic active ingredient worldwide.
Pentylene glycol is initially based on the immature juice of sugar beets, while synthetic production is standard.
Pentylene glycol is used in day and night creams.
Pentylene glycol is a complex system for paraben esters-free cosmetic and personal care products.
Pentylene glycol is a multifunctional agent that has excellent efficacy as a biostatic and fungistatic agent.
Pentylene glycol can reduce irritation and sensitivity and has a wide broad-spectrum antimicrobial effect.
Pentylene glycol is an ingredient which is found naturally in some plants (such as sugar beets and corn cobs) but is most frequently lab-derived when used in cosmetics.
Pentylene glycol is a humectant, meaning it binds well to water, making Pentylene glycol a good hydrating agent and solvent to aid penetration of other ingredients.
Pentylene glycol also helps improve the texture of skin care formulas and has mild preservative properties when used in amounts between 1-5%.
There have been some reports that Pentylene glycol (along with other glycols) is a skin sensitizer; however, as with many ingredients, the amount and how it’s used are key.
Pentylene glycol is a chemical compound commonly used in the cosmetics and personal care industry as a skincare and beauty product ingredient.
Pentylene glycol is also known by its chemical formula C5H12O2.
Pentylene glycol is a type of glycol, which is a class of organic compounds that contain multiple hydroxyl (OH) groups.
Pentylene glycol proves multifunctional in skincare and cosmetic formulations, offering a spectrum of benefits.
With its hydrating properties, Pentylene glycol serves as an effective moisturizer, aiding in maintaining skin moisture levels, particularly beneficial for individuals with dry or dehydrated skin.
Acting as a solvent, Pentylene glycol ensures a consistent and uniform texture in products by dissolving other ingredients.
Pentylene glycol antimicrobial properties contribute to its role as a preservative, preventing the growth of bacteria and fungi and enhancing Pentylene glycol’s longevity.
Recognized for Pentylene glycol mild and non-irritating nature, Pentylene glycol is considered suitable for sensitive skin.
Additionally, Pentylene glycol facilitates the penetration of active ingredients, amplifying the efficacy of skincare formulations.
Overall, Pentylene glycol is a versatile ingredient, addressing various aspects of skincare, from hydration and preservation to compatibility with different skin types.
Pentylene glycol is generally recognized as safe for use in cosmetics and skincare products when used in accordance with regulations and guidelines.
However, as with any ingredient, individual reactions or sensitivities may vary, so it’s essential to check Pentylene glycol’s ingredients list and perform a patch test if you have sensitive skin or allergies.
Uses of Pentylene glycol:
Pentylene glycol is used as an emulsion stabilizer, humectant, solvent and a broad-spectrum antimicrobial.
Pentylene glycol improves texture of the product.
Pentylene glycol has all the characteristics of a solvent.
Pentylene glycol is not reactive and can dissolve many other compounds.
Pentylene glycol is also known to have antimicrobial properties.
Pentylene glycol offers a double advantage:
Pentylene glycol protects the skin from harmful bacteria, which could otherwise cause body odor and acne problems on the skin.
Secondly, Pentylene glycol protects the product from any microbial growth, so Pentylene glycol can show the same quality during its use and shelf life.
Skin care:
Due to the two -OH groups, Pentylene glycol has a natural tendency to attract water.
Pentylene glycol also retains water, which is especially helpful for dry skin.
Pentylene glycol is used as a humectant and skin conditioning agent, for Pentylene glycol ability to retain moisture.
Pentylene glycol is used in moisturizer, baby sunscreen, around-eye cream, antiperspirant/deodorant, serums & essences, hand cream, anti-aging, facial moisturizer/treatment, detanning products, bath oil/salts/soak, body oil, body firming lotion, cuticle treatment, body wash/cleanser, tanning oil, recreational sunscreen
Hair care:
Pentylene glycol is used in various hair care products such as hair treatment/serum, hair spray, hair styling aide, shampoo, detangler, beard care, shaving cream, beard oil, conditioner, hair color and bleaching, styling gel/lotion, mask, setting powder/spray
Decorative cosmetics:
Pentylene glycol is used in cosmetics such as lipstick, concealer, eye shadow, foundation, CC cream, blush, lip balm, facial powder, bronzer/highlighter, lip gloss, BB cream, makeup primer, brow liner, lip liner, eye liner, lip plumper, lip balm, makeup remover
Uses Area of Pentylene glycol:
Pentylene glycol is used as a solvent in chemicals produced in the cosmetic industry to soften and smooth the skin.
Pentylene glycol has a softening and smoothing effect in this area of use.
Pentylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, 1,3-butylene glycol and Mono Propylene Glycol are also used as solvents.
This is because 1,3-butylene glycol and Mono Propylene Glycol do not have completely toxic effects.
Pentylene glycol is used by combining anti-inflammatory hydrocortisone with pylene glycol to relieve minor skin irritation, temporary itching and inflammation.
Pentylene glycol is used in the production of allergy medications.
Pentylene glycol has antimicrobial properties because Pentylene glycol is Dihydric Alcohol.
Pentylene glycol helps prevent unwanted microorganisms due to Pentylene glycol antimicrobial effect.
Pentylene glycol is preferred in the production of quality cosmetic products because Pentylene glycol allergic effects are very low.
Pentylene glycol is used in the manufacture of daily skin care products due to Pentylene glycol moisturizing effect on the skin.
By retaining water on the skin, Pentylene glycol makes the skin more vibrant, smooth and plump.
Pentylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetics industry.
Pentylene glycol has a softening and smoothing effect in this area of use.
Pentylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, Pentylene glycol and Mono Propylene Glycol are also used as solvents.
This is because Pentylene glycol and Mono Propylene Glycol do not have exactly the toxic effects.
Pentylene glycol is used to relieve minor skin irritation, temporary itching and inflammation, by combining the anti-inflammatory hydrocortisone with pylenylene glycol.
Pentylene glycol is used in the production of allergy medicines.
Pentylene glycol has antimicrobial properties due to being dihydric alcohol.
Due to Pentylene glycol antimicrobial effect, Pentylene glycol helps to prevent unwanted microorganisms.
Pentylene glycol is preferred in the manufacture of quality cosmetic products because of Pentylene glycol very low allergic effects.
Pentylene glycol is used in the manufacture of daily skin care products due to its moisturizing effect on the skin.
By keeping the water on the skin, Pentylene glycol makes the skin more lively, smooth and full.
Applications of Pentylene glycol:
Pentylene glycol has a wide range of applications.
Intermediate finds applications in Initial product for chemical syntheses, Inks and coatings, Plasticizers and Solvent, Industrial chemicals.
Pentylene glycol is used as a plasticizer in cellulose products and adhesives.
Pentylene glycol is used as a brake fluid additive.
Pentylene glycol reacts with 3,4-dihydro-2H-pyran to get 5-tetrahydropyran-2-yloxy-pentan-1-ol.
Pentylene glycol is also used to prepare polyesters for emulsifying agents and resin intermediates.
Pentylene glycol is used in ink, toner and colorant products.
In addition to this, Pentylene glycol is used in brake fluid compositions.
Pentylene glycol is used to produce materials made of polyester or polyurethane, for the manufacturing of monomers, for the manufacture of polyester polyols, polycarbonatedioles and acrylic monomers, for the production of delta valerolactone and for molecules that act as reactive diluents, for the production of halogenated substances and for the production of adhesives, putties and sealing compounds, cleaners and auxiliary agents.
Pentylene glycol is used in the processes to produce hydrogen, hydrogen peroxide, sodium perborate and peroxyacetic acid and as an intermediate for pharmaceutical products.
Pentylene glycol is used as an ingredient for the production of polymeric thickeners, plasticizers for polyvinyl chloride, sizing agents, surfactants, for starches and chemically modified starch for application in the paper, textile and food industry, for personal hygiene products like shampoo, creams, and for paints.
Benefits of Pentylene glycol:
Pentylene glycol naturally tends to attract water because Pentylene glycol has two -OH groups.
Pentylene glycol also retains water, which is especially beneficial for dry skin.
Pentylene glycol is used as a humidifier due to its moisture retention capacity.
Pentylene glycol has all the properties of a solvent.
Pentylene glycol is non-reactive and can dissolve many other compounds.
As mentioned before, due to Pentylene glycol ability to naturally retain moisture in the skin, Pentylene glycol also nourishes the skin and hair.
Pentylene glycol is also known to have antimicrobial properties.
Pentylene glycol offers a double advantage – Pentylene glycol protects the skin from harmful bacteria that can otherwise cause body odor and acne problems on the skin.
Secondly, Pentylene glycol protects the product from microbial growth, so that Pentylene glycol can maintain the same quality throughout its use and shelf life.
Pentylene glycol is used in the formulations of creams, lotions, moisturizers, cleansers and other skin care products.
Pentylene glycol offers several benefits when used in skincare and cosmetic products:
Moisturization:
Pentylene glycol helps to hydrate the skin by retaining moisture, making Pentylene glycol beneficial for individuals with dry or dehydrated skin.
Solvent:
Pentylene glycol serves as a solvent for various cosmetic ingredients, ensuring that the product has a uniform texture and consistency.
Preservation:
Pentylene glycol has antimicrobial properties, which help prevent the growth of harmful microorganisms like bacteria and fungi in cosmetic products, extending their shelf life.
Skin-Friendly:
Pentylene glycol is known for being mild and non-irritating, making Pentylene glycol suitable for sensitive skin types and reducing the risk of skin irritation or allergic reactions.
Enhanced Ingredient Penetration:
Pentylene glycol can improve the absorption of other active ingredients into the skin, increasing the effectiveness of skincare formulations.
Peoduction of Pentylene glycol:
Pentylene glycol is produced synthetically from corn and sugar cane.
Origin of Pentylene glycol:
Pentylene glycol is based on by-products from manufacturing processes based on sugarcane residues and corn spindles.
However, Pentylene glycol is manufactured in the lab as the consumption is relatively high.
Effect of Pentylene glycol in the formulation:
antimicrobial
Emulsion stabilization
Moisturizer
Solvent
Physical And Chemical Properties of Pentylene glycol:
Pentylene glycol is a physically colorless oil-free liquid.
The density of Pentylene glycol is 0.994 g/mol.
The melting point of Pentylene glycol is -18 °C.
Pentylene glycol is a stable chemical.
Pentylene glycol should be stored at room temperature.
Pentylene glycol is soluble in water.
Safety profile of Pentylene glycol:
Pentylene glycol does not have any evidence to suggest hazardous to health, toxicity, or carcinogenicity.
Pentylene glycol has been found to cause mild irritation to the eyes and skin in skin types that are already sensitized or prone to irritation.
Health Effect of Pentylene glycol:
Pentylene glycol is a semi-synthetic component.
The starting raw materials are of natural origin, but are transformed into a different form than their original state using various processes under laboratory conditions.
These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).
Pentylene glycol is a criterion that should be taken into consideration for those who want to use vegan products.
Studies have concluded that different effects can be seen on each skin type.
For this reason, the allergy/irritation effect may vary from person to person.
However, Pentylene glycol may cause reactions such as stinging, tingling, itching, redness, irritation, skin flaking and swelling, especially in people with sensitive skin types.
Identifiers of Pentylene glycol:
CAS Number: 5343-92-0
Chem/IUPAC Name: 2-heptanoyloxypentyl heptanoate
EINECS/ELINCS No: 226-285-3
COSING REF No: 58983
Molecular Formula (Pentylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol
Chemical Name: 1,2-Pentanediol
CAS Number: 5343-92-0
Properties of Pentylene glycol:
form: solution
mol wt: Mr ~1500
packaging: pkg of 10 × 4 mL
manufacturer/tradename: Roche
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: C(CO)O
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
Other Names of Pentylene glycol:
IUPAC Names:
1,5-Pentanediol
1,5-pentanediol
Pentamethylene glycol
pentane,-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentanediol
