PHENOXYPROPANOL

Phenoxypropanol is a versatile and widely used chemical compound that plays a crucial role in a variety of applications, particularly in the cosmetic, pharmaceutical, and industrial sectors.

Phenoxypropanol’s ability to function as a preservative and antimicrobial agent makes it invaluable in cosmetics, where it helps to extend the shelf life of products by preventing the growth of bacteria, mold, and yeast.

In the pharmaceutical industry, phenoxypropanol serves as a stabilizer and preservative, ensuring the longevity and safety of medications.

CAS Number: 122-99-6

EC Number: 212-222-7

Molecular Formula: C9H12O2

Molar mass: 138.166 g·mol−1

Synonyms: 1-Phenoxy-2-propanol, 1-Phenoxy-2-propanol, 1-Phénoxy-2-propanol, 1-Phenoxypropan-2-ol, 2-Propanol, 1-phenoxy-212-222-7, 41593-38-8, 87CZY0NY1A, DOWANOL(R) PPh, MFCD00016861, phenoxy-propan-2-ol (mixed isomer), Phenoxyisopropanol, Propylene glycol phenyl ether, Propylene phenoxytol, (2S)-1-Phenoxy-2-propanol, (±)-1-PHENOXYPROPAN-2-OL, 1,2-PROPANEDIOL,(S)-FORM,1-PH ETHER, 1-(phenoxy)propan-2-ol, 1-PHENOXY-2-HYDROXYPROPANE, 1-Phenoxy-2-propanol, tech., 130879-97-, 2-Phenoxy-1-methylethanol, 770-35-4, 95%, DOWANOL PPh, Phenoxypropanol, Phenyl-β-hydroxypropyl ether, propan-2-ol, 1-phenoxy-, Propylene glycol monophenyl ether, PROPYLENE PHENOXETOL, propylene phenoxytol, reagent, Propylenephenoxythol, 1-Phenyl-1-propanol, 1-Phenylpropan-1-ol, 93-54-9, Phenylpropanol, 1-Phenylpropanol, Phenycholon, Fepar, Ejibil, Felicur, Livonal, 1-Phenylpropyl alcohol, Gallenperlen, Phenylchol, Bilergon, Carbicol, Choleda, Epatoxfen, Felitrope, Phenicol, Phenychol, Unichol, Phenyl ethyl carbinol, Phenylcholon, alpha-Ethylbenzyl alcohol, Ethyl phenyl carbinol, 1-Propanol, 1-phenyl-, 1-Phenyl-1-hydroxypropane, Phenylpropanol [JAN], FEMA No. 2884, SH 261, Phenylaethylcarbinol, phenyl propanol, Benzenemethanol, .alpha.-ethyl-, .alpha.-Ethylbenzyl alcohol, NSC 25504, Benzyl alcohol, .alpha.-ethyl-, 1-Phenyl-propan-1-ol, MFCD00004564, NSC-25504, .alpha.-Hydroxypropylbenzene, .omega.-Ethylbenzyl alcohol, DTXSID2044474, 0F897O3O4M, Phenylpropanol (JAN), NCGC00165972-01, alpha-Ethylbenzenemethanol, Fenicol (VAN), alpha-Hydroxypropylbenzene, ETHYLPHENYLCARBINOL, Phenylaethylcarbinol [German], Benzenemethanol, alpha-ethyl-, a-ethylbenzyl alcohol, R-(+)-1-Phenylpropanol, S-(-)-1-Phenylpropanol, (R)-1-phenyl-1-propanol, BENZYL ALCOHOL, alpha-ETHYL-, EINECS 202-256-0, BRN 1906759, UNII-0F897O3O4M, AI3-19819, Phenylpropylalkohol, Ethylbenzyl alcohol, 1-Phenyl-n-propanol, a-Hydroxypropylbenzene, Other proprietary names, 1- phenyl-1-propanol, Phenyl-1-propan-1-ol, alpha-Ethyl-benzyl alcohol, 1-hydroxy-1-phenylpropane, (+/-)-1-Phenylpropanol, EC 202-256-0, .alpha.-Ethylbenzenemethanol, a-Ethylbenzenemethanol, 9CI, SCHEMBL56673, ghl.PD_Mitscher_leg0.415, 4-06-00-03183 (Beilstein Handbook Reference), PHENYLPROPANOL [MART.], (+/-) 1-phenyl-1-propanol, CHEMBL1397202, DTXCID0024474, CHEBI:31995, FEMA 2884, 1-Phenyl-1-propanol, >=97%, NSC25504, NSC41708, STR02714, Tox21_112275, 1-PHENYL-1-PROPANOL [FHFI], ETHYLBENZYL ALCOHOL [WHO-DD], NSC-41708, 1-Phenyl-1-propanol, >=97%, FG, AKOS000249117, AKOS016843880, AB88253, CS-W013334, HY-W012618, CAS-93-54-9, s11247, NCGC00165972-02, NCGC00165980-01, NCGC00166078-01, .ALPHA.-ETHYLBENZYL ALCOHOL [MI], DA-66667, SY020321, SY101126, DB-043324, DB-072950, NS00004787, P0212, D01470, EN300-128217, SBI-0654040.0001, SR-01000944521, ( inverted exclamation markA)-1-Phenyl-1-propanol, Q-200134, SR-01000944521-1, Q15726117, Z335245178

Phenoxypropanol is a synthetic organic compound commonly used as a preservative, solvent, and stabilizer in various industrial, cosmetic, and pharmaceutical products.

Phenoxypropanol appears as a colorless to pale yellow liquid with a mild, pleasant odor and is known for its solubility in water, alcohol, and a variety of organic solvents.

With the chemical formula C9H12O2 and a molecular weight of 152.19 g/mol, phenoxypropanol serves multiple functions, including as an antimicrobial agent, solvent for essential oils, and stabilizer in personal care products like lotions, shampoos, deodorants, and facial creams.

Additionally, Phenoxypropanol finds applications in the pharmaceutical industry for preserving medications and enhancing the stability of formulations.

Although generally considered safe when used in concentrations of up to 1% in cosmetics, excessive exposure to phenoxypropanol can cause skin irritation, particularly in sensitive individuals.

Phenoxypropanol is also flammable, so care should be taken to avoid open flames and prolonged exposure to high concentrations.

Phenoxypropanol is prized for its effectiveness in preventing microbial contamination, ensuring product safety and longevity, and is often included in formulations where preservation and stability are crucial.

Phenoxypropanol’s versatility also extends to being a solvent in some pesticide formulations and a stabilizing agent in various chemical processes, making it a valuable component across multiple industries.

Phenxoypropanol, a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst.

The influence of Phenoxypropanol’s anesthetic property on gastropods has been analyzed.

Phenoxypropanol’s degradation by microorganisms in different soil types has been investigated.

Phenxoypropanol is an antimicrobial agent that belongs to the group of glycol ethers.

Phenoxypropanol has a hydroxyl group and atp levels, which are both vital for its activity index.

Phenxoypropanol is used as a preservative in cosmetics and pharmaceuticals, with the exception of eye products.

Phenoxypropanol also has been shown to have a low level of toxicity for humans and other mammals, such as rats and guinea pigs.

The EPA has classified Phenoxypropanol as Group D – not classifiable as to human carcinogenicity.

Phenoxypropanol is toxic to bacteria, yeast, fungi, algae, plants, and invertebrates when present in high concentrations.

Phenoxypropanol is a colorless oily liquid.

Phenoxypropanol can be classified as a glycol ether and a phenol ether.

Phenoxypropanol is a common preservative in vaccine formulations.

Phenoxypropanol has a faint rose-like aroma.

Phenoxypropanol is a versatile and widely used chemical compound that plays a crucial role in a variety of applications, particularly in the cosmetic, pharmaceutical, and industrial sectors.

This clear, colorless to pale yellow liquid with a mild, pleasant odor is favored for Phenoxypropanol’s stability and solubility in water, alcohol, and organic solvents.

Phenoxypropanol’s ability to function as a preservative and antimicrobial agent makes it invaluable in cosmetics, where it helps to extend the shelf life of products by preventing the growth of bacteria, mold, and yeast.

Commonly found in products such as skin lotions, shampoos, deodorants, sunscreens, and facial creams, phenoxypropanol enhances both the safety and efficacy of these formulations by ensuring they remain free from harmful microorganisms throughout their use.

In the pharmaceutical industry, phenoxypropanol serves as a stabilizer and preservative, ensuring the longevity and safety of medications.

Phenoxypropanol is also used as a solvent for essential oils, which further expands its utility in the creation of perfumes, fragrances, and other specialty products.

Phenoxypropanol is sometimes included in pesticide formulations as well, owing to its solvent properties that help to dissolve active ingredients and facilitate their application.

Although generally considered safe for topical use in concentrations of up to 1%, phenoxypropanol may cause skin irritation or allergic reactions in some sensitive individuals, making it important to follow usage guidelines.

Furthermore, Phenoxypropanol is flammable, so caution is required to avoid ignition, especially in environments with high temperatures or open flames.

As a result of its diverse functions, phenoxypropanol remains a crucial ingredient in ensuring the performance, safety, and stability of a wide range of consumer and industrial products.

Uses of Phenoxypropanol:

Phenoxypropanol is a highly versatile chemical compound widely used in cosmetics, pharmaceuticals, and industrial applications due to its antimicrobial, solvent, and stabilizing properties.

In cosmetics and personal care products, Phenoxypropanol serves as a preservative to extend shelf life by preventing microbial growth in items such as lotions, shampoos, deodorants, and facial creams.

Additionally, Phenoxypropanol acts as a solvent for essential oils and a stabilizer in formulations, ensuring consistency and effectiveness.

In the pharmaceutical industry, phenoxypropanol is employed as a preservative in medications and as a solvent for active ingredients, enhancing the stability and safety of pharmaceutical products.

Phenoxypropanol’s use extends to pesticide formulations, where it helps dissolve and stabilize active ingredients, as well as in metal cleaning products, where it functions as a dispersing agent.

Phenoxypropanol is also used in perfumes, fragrances, and essential oils to facilitate better blending of aromatic compounds.

With applications in food and beverage products as a preservative, and even in toothpaste for tartar control, phenoxypropanol demonstrates its widespread utility across numerous sectors.

Phenoxypropanol’s multifunctional role makes it an indispensable ingredient in many consumer and industrial formulations.

Phenoxypropanol is often used together with quaternary ammonium compounds.

Phenoxypropanol is an alternative to formaldehyde-releasing preservatives.

In Japan and the European Union, Phenoxypropanol’s concentration in cosmetics is restricted to 1%.

Phenoxypropanol has a broad range of applications, primarily in cosmetics, pharmaceuticals, and industrial formulations.

Below are the key uses of phenoxypropanol:

Cosmetics and Personal Care:

Preservative:

Phenoxypropanol is widely used as a preservative in cosmetics and personal care products, such as lotions, shampoos, deodorants, sunscreens, facial creams, and make-up.

Phenoxypropanol helps to prevent the growth of bacteria, mold, and yeast, extending the shelf life of these products.

Antimicrobial Agent:

Phenoxypropanol has antimicrobial properties that make it effective at maintaining the integrity and safety of products by controlling microbial contamination.

Solvent and Stabilizer:

In addition to its preservative role, phenoxypropanol acts as a solvent for essential oils and other compounds, as well as a stabilizer in formulations that require consistency and durability.

Pharmaceuticals:

Preservative in Medicines:

Phenoxypropanol is used as a preservative in pharmaceutical products to help maintain the stability and safety of medications, preventing microbial contamination.

Solvent for Active Ingredients:

Phenoxypropanol is also employed as a solvent for active ingredients in pharmaceutical formulations, enhancing the dissolution and stability of certain compounds.

Industrial Applications:

Pesticide Formulations:

Due to its solvent properties, phenoxypropanol is used in certain pesticide formulations to dissolve and stabilize active ingredients, making it easier to apply and more effective in pest control.

Metal Cleaning:

Phenoxypropanol is used in cleaning agents for metal surfaces, where it acts as a dispersing agent, helping to remove dirt, grease, and other contaminants.

Fragrances and Essential Oils:

Solvent in Fragrances:

Phenoxypropanol is used in perfumes and fragrances as a solvent to dissolve essential oils and other aromatic compounds, allowing them to blend more effectively in the final product.

Food and Beverages:

Food Additive:

While less common, phenoxypropanol is sometimes utilized in food and beverage formulations as a preservative or stabilizer to extend product shelf life.

Other Uses:

Tartar Control in Toothpastes:

Phenoxypropanol acts as a tartar control agent in toothpastes by helping to remove calcium and magnesium from saliva, which can contribute to tartar formation on teeth.

Water Treatment:

In some water treatment formulations, phenoxypropanol serves as a dispersing agent to help maintain the stability and effectiveness of the treatment solution.

Industry Uses:

Solvents (which become part of product formulation or mixture)

Other (specify)

Anti-adhesive/cohesive

Adhesives and sealant chemicals

Not Known or Reasonably Ascertainable

Solvent

Processing aids, not otherwise listed

Consumer Uses:

Other (specify)

Lubricants and lubricant additives

Anti-adhesive/cohesive

Adhesives and sealant chemicals

Not Known or Reasonably Ascertainable

Solvent

Benefits of Phenoxypropanol:

Phenoxypropanol offers a variety of benefits, particularly in the fields of cosmetics, pharmaceuticals, and industrial applications.

Some of the key benefits include:

Effective Preservative:

Phenoxypropanol is a powerful preservative that helps extend the shelf life of products by preventing the growth of bacteria, mold, and yeast.

This is crucial in personal care products like lotions, shampoos, deodorants, and facial creams, ensuring that they remain safe for use over time.

Antimicrobial Properties:

Due to its antimicrobial action, phenoxypropanol is effective in protecting products from microbial contamination.

Phenoxypropanol helps maintain product integrity and safety, reducing the risk of infection or skin irritation caused by harmful microorganisms.

Solvent and Stabilizer:

In addition to its preservative function, phenoxypropanol acts as a solvent for essential oils and other organic compounds, making it useful in the formulation of fragrances, perfumes, and other specialty products.

Phenoxypropanol also functions as a stabilizer, ensuring the uniformity and consistency of formulations.

Non-Irritating for Most Skin Types:

Phenoxypropanol is generally considered safe for topical use, with low risk of skin irritation or sensitization when used in appropriate concentrations (typically up to 1%).

This makes it a suitable option for sensitive skin care products.

Versatility:

Phenoxypropanol is highly versatile and finds applications in a wide range of products, including cosmetics, pharmaceuticals, cleaning agents, and even pesticide formulations.

Phenoxypropanol is especially useful in multi-functional formulations due to its ability to serve as both a preservative and a solvent.

Environmental Safety:

Phenoxypropanol is biodegradable, making it an environmentally friendly option compared to some other preservatives and solvents that may accumulate in the environment.

This property is especially important for manufacturers focused on sustainability.

Tartar Control in Oral Care:

In oral care products like toothpaste, phenoxypropanol is used as a tartar control agent.

Phenoxypropanol helps prevent the deposition of calcium and magnesium on teeth, which are responsible for the formation of tartar, thus promoting oral hygiene and dental health.

Enhances Product Performance:

In cleaning agents and other industrial formulations, phenoxypropanol acts as a dispersing agent, improving the effectiveness of products by helping to dissolve and distribute active ingredients more efficiently.

Phenoxypropanol is also used in metal cleaning and water treatment solutions.

Overall, phenoxypropanol is valued for its broad-spectrum antimicrobial properties, versatility in formulations, and environmental safety, making it a beneficial ingredient across various industries.

Production of Phenoxypropanol:

Phenoxypropanol is produced through a synthetic process that typically involves the reaction of phenol with 1-chloropropan-2-ol.

In this reaction, phenol, an aromatic compound, reacts with 1-chloropropan-2-ol in the presence of a base, such as sodium hydroxide, to facilitate a nucleophilic substitution.

The phenol’s hydroxyl group attacks the electrophilic carbon in the 1-chloropropan-2-ol, displacing the chloride ion and forming phenoxypropanol.

This process is carried out under controlled conditions of temperature and pressure to ensure high yield and purity.

After the reaction, the crude product is purified through methods like distillation or solvent extraction to remove impurities and unreacted starting materials.

The final, purified phenoxypropanol is then dried and tested for quality before being formulated for use in a variety of products, such as cosmetics, pharmaceuticals, and industrial applications.

This cost-effective production method ensures that phenoxypropanol is widely available for use as a preservative, solvent, and stabilizer in many different sectors.

General Manufacturing Information of Phenoxypropanol:

Industry Processing Sectors:

Miscellaneous Manufacturing

Textiles, apparel, and leather manufacturing

Adhesive Manufacturing

Paint and Coating Manufacturing

All Other Basic Organic Chemical Manufacturing

Not Known or Reasonably Ascertainable

Printing and Related Support Activities

Mechanism of Action of Phenoxypropanol:

Cell Membrane Disruption:

Phenoxypropanol has a hydrophobic (water-repelling) nature, which allows it to interact with the lipid bilayer of bacterial cell membranes.

Phenoxypropanol can insert itself into the membrane, causing structural changes and increasing its permeability.

This disrupts the membrane’s integrity, leading to leakage of cellular contents, which can be fatal to the microorganism.

Inhibition of Enzyme Activity:

As a preservative, phenoxypropanol can interfere with the enzymatic systems of microorganisms.

Enzymes that are critical for energy production, cell division, or other vital functions may be inhibited, which disrupts the microorganism’s ability to grow and replicate.

Interference with Protein Synthesis:

Phenoxypropanol may also disrupt protein synthesis within microbial cells by affecting ribosomal function or interfering with the processes involved in translating genetic material into functional proteins.

This results in the inhibition of microbial growth and reproduction.

Sequestering of Metal Ions:

In some cases, phenoxypropanol may act as a chelating agent, binding to essential metal ions in microbial cells, which are required for various metabolic processes.

By sequestering these metal ions, phenoxypropanol deprives the microorganisms of the necessary resources for growth.

Additional Mechanisms in Industrial Use:

As a solvent, phenoxypropanol can dissolve hydrophobic substances like essential oils and other active compounds, aiding in their distribution and stability in formulations.

Phenoxypropanol is not as active against all pathogens and typically works best in combination with other preservatives to provide broad-spectrum antimicrobial protection.

In summary, phenoxypropanol acts through a combination of membrane disruption, enzyme inhibition, interference with protein synthesis, and metal ion sequestering to prevent the growth of microorganisms, making it an effective preservative and antimicrobial agent.

History and Synthesis of Phenoxypropanol:

Phenoxyethanol was first prepared by W. H. Perkin Jr. and his graduate student Edward Haworth in 1896.

They reacted sodium, phenol and 2-chloroethanol in anhydrous ethanol.

Starting from the 1920s, Phenoxypropanol has been commercially available as a cellulose acetate solvent under the trademark of “Phenyl cellosolve”.

Phenoxypropanol is produced in the industry by the hydroxyethylation of phenol (Williamson synthesis), for example, in the presence of alkali-metal hydroxides or alkali-metal borohydrides.

Handling and Storage of Phenoxypropanol:

Handling:

Use phenoxypropanol in well-ventilated areas to minimize inhalation exposure.

Avoid direct contact with skin and eyes.

Handle Phenoxypropanol in accordance with good industrial hygiene practices.

Do not eat, drink, or smoke while handling phenoxypropanol.

Storage:

Store in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat.

Keep containers tightly closed to prevent contamination or degradation.

Ensure the storage area is secure and well-marked, with appropriate spill containment measures.

Avoid storing with incompatible materials such as strong acids or oxidizing agents.

Reactivity and Stability of Phenoxypropanol:

Stability:

Phenoxypropanol is generally stable under normal conditions of use and storage.

Phenoxypropanol is stable in the presence of air and moisture but should be kept away from extreme temperatures and direct sunlight.

Reactivity:

Phenoxypropanol is not highly reactive but should be kept away from strong acids, bases, and oxidizers to prevent possible reactions that could lead to hazardous situations.

Decomposes at high temperatures, which may release toxic gases.

First Aid Measures

Inhalation:

If inhaled, move the person to fresh air immediately.

Seek medical attention if symptoms persist, such as coughing, shortness of breath, or irritation.

Skin Contact:

Wash the affected area with soap and water for at least 15 minutes.

Remove contaminated clothing.

If irritation occurs, seek medical attention.

Eye Contact:

Immediately flush eyes with water for at least 15 minutes, lifting the upper and lower eyelids.

Seek medical attention if irritation persists.

Ingestion:

If swallowed, do not induce vomiting unless instructed by a medical professional.

Rinse mouth with water and drink water or milk to dilute.

Seek immediate medical attention.

Firefighting Measures of Phenoxypropanol:

Extinguishing Media:

Use water spray, foam, dry chemical, or carbon dioxide (CO₂) to extinguish fires.

Firefighting Instructions:

Wear self-contained breathing apparatus (SCBA) and full protective clothing to avoid exposure to hazardous combustion products.

Avoid direct water streams to prevent spreading of fire.

In the event of a fire, cool containers with water to prevent rupture.

Hazards from Combustion:

Combustion may produce harmful gases, such as carbon monoxide, carbon dioxide, and other toxic compounds.

Accidental Release Measures of Phenoxypropanol:

Personal Precautions:

Evacuate the area and ventilate.

Wear appropriate protective equipment, including gloves, goggles, and a respirator if necessary.

Environmental Precautions:

Prevent spillage from entering drains, sewers, or water sources.

If Phenoxypropanol contaminates waterways, notify the appropriate environmental authorities immediately.

Clean-Up:

Contain the spill with inert material (e.g., sand, earth) and collect it into a suitable container for disposal.

Clean the affected area thoroughly with water and detergents.

Ensure proper disposal according to local regulations for hazardous waste.

Exposure Controls/Personal Protective Equipment of Phenoxypropanol:

Occupational Exposure Limits:

Ensure that the concentration of phenoxypropanol in the workplace does not exceed recommended exposure limits.

Refer to local regulatory guidelines for specific limits.

Engineering Controls:

Use local exhaust ventilation or mechanical ventilation to control airborne concentrations of phenoxypropanol.

Personal Protective Equipment:

Eye Protection:

Wear safety goggles or face shield to prevent splashes into eyes.

Skin Protection:

Wear gloves, protective clothing, and boots to minimize skin contact.

Respiratory Protection:

If exposure limits are exceeded, wear an approved respirator (e.g., N95 or P100) for protection against inhalation of vapors or dust.

General Hygiene:

Wash hands and exposed skin thoroughly after handling phenoxypropanol, especially before eating, drinking, or smoking.

Avoid direct contact with eyes and skin, and take necessary precautions to prevent inhalation of vapors or dust.

Identifiers of Phenoxypropanol:

CAS Number: 122-99-6

ChEBI: CHEBI:64275

ChEMBL: ChEMBL1229846

ChemSpider: 13848467

ECHA InfoCard: 100.004.173

PubChem CID: 31236

UNII: HIE492ZZ3T

CompTox Dashboard (EPA): DTXSID90873407 DTXSID9021976, DTXSID90873407

InChI: InChI=1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2

Key: QCDWFXQBSFUVSP-UHFFFAOYSA-N

InChI=1/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2

Key: QCDWFXQBSFUVSP-UHFFFAOYAU

SMILES: c1ccc(cc1)OCCO

Product Number: P0118

Purity / Analysis Method: >95.0%(GC)

Molecular Formula / Molecular Weight: C9H12O2 = 152.19 

Physical State (20 deg.C): Liquid

Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C) Store Under Inert Gas: Store under inert gas Condition to Avoid: Air Sensitive CAS RN: 770-35-4 Reaxys Registry Number: 1941356 PubChem Substance ID: 87574373 SDBS (AIST Spectral DB): 6395 MDL Number: MFCD00016861 Condition to Avoid: Air Sensitive EC Number: 212-222-7 Physical State (20 deg.C): Liquid PubChem Substance ID: 87574373 Purity(GC): min. 95.0 % Reaxys Registry Number: 1941356 Refractive Index: 1.52 SDBS (AIST Spectral DB): 6395 Signal Word: Danger Store Under Inert Gas: Store under inert gas Quality Level: 100 Assay: ≥93% impurities: <7% di(propylene glycol) phenyl ether refractive index: n20/D 1.523 (lit.) bp: 243 °C (lit.) density: 1.064 g/mL at 20 °C (lit.) SMILES string: CC(O)COc1ccccc1 InChI: 1S/C9H12O2/c1-8(10)7-11-9-5-3-2-4-6-9/h2-6,8,10H,7H2,1H3 InChI key: IBLKWZIFZMJLFL-UHFFFAOYSA-N Properties of Phenoxypropanol: Chemical formula: C8H10O2 Molar mass: 138.166 g·mol−1 Appearance: Colorless oily liquid Odor: faint rose-like Density: 1.102 g/cm3 Melting point: −2 °C (28 °F; 271 K) Boiling point: 247 °C (477 °F; 520 K) Solubility in water: 26 g/kg Solubility: Chloroform, Alkali, diethyl ether: soluble Solubility in peanut oil: slightly Solubility in olive oil: slightly Solubility in acetone: miscible Solubility in ethanol: miscible Solubility in glycerol: miscible Vapor pressure: 0.001 kPa (0.00015 psi) Thermal conductivity: 0.169 W/(m⋅K) Refractive index (nD): 1.534 (20 °C) Appearance: Colorless - slightly yellow, clear liquid Boiling Point: 243 degrees C Flash Point: 135 degrees C Density: 1.060 - 1.068g/ml(20 degrees C) Specific Gravity: 1.051 Refractive Index: 1.519 - 1.527(20 degrees C/D) Molecular Weight: 136.19 g/mol XLogP3: 1.9 Hydrogen Bond Donor Count: 1 Hydrogen Bond Acceptor Count: 1 Rotatable Bond Count: 2 Exact Mass: 136.088815002 Da Monoisotopic Mass: 136.088815002 Da Topological Polar Surface Area: 20.2Ų Heavy Atom Count: 10 Complexity: 84.7 Isotope Atom Count: 0 Defined Atom Stereocenter Count: 0 Undefined Atom Stereocenter Count: 1 Defined Bond Stereocenter Count: 0 Undefined Bond Stereocenter Count: 0 Covalently-Bonded Unit Count: 1 Compound Is Canonicalized: Yes Related compound of Phenoxypropanol: phenetole Names of Phenoxypropanol: Preferred IUPAC name: 2-Phenoxyethan-1-ol Other names: Phenoxyethanol Ethylene glycol monophenyl ether Phenoxytolarosol Dowanol EP / EPH Protectol PE Emery 6705 Rose ether 1-Hydroxy-2-phenoxyethane β-hydroxyethyl phenyl ether Phenyl cellosolve Phenoxetol®