STEARYL ALCOHOL
STEARYL ALCOHOL
Stearyl alcohol is waxy solid alcohol formerly obtained from whale or dolphin oil and used as a lubricant and antifoam agent and to retard evaporation of water from reservoirs.
Stearyl alcohol is used as an opacifying agent and foaming surfactant, as well as an aqueous and non-aqueous viscosity increasing agent.
Stearyl alcohol is a vegetable-derived ingredient that’s naturally found in plants, insects, and even humans.
CAS Number: 112-92-5
EC Number: 204-017-6
Chemical Formula: C18H38O
Molar Mass: 270.49 g/mol
Synonyms: Stearyl alcohol, Octadecan-1-ol, 1-OCTADECANOL, Octadecanol, 112-92-5, 1-Hydroxyoctadecane, Octadecyl alcohol, n-Octadecanol, n-1-Octadecanol, Stearol, n-Octadecyl alcohol, Stearic alcohol, Atalco S, Alfol 18, Steraffine, Alcohol stearylicus, Polaax, Stenol, Crodacol-S, Siponol S, Siponol SC, Aldol 62, Lanol S, Sipol S, Adol 68, Decyl octyl alcohol, Cachalot S-43, Lorol 28, 1-0ctadecanol, Dytol E-46, Stearylalkohol, Usp xiii stearyl alcohol, Octadecylalkohol, C18 alcohol, Rita SA, Lanette 18, Hainol 18SS, Alcohol(C18), Custom stearyl, CO-1895, Ultrapure s, Oristar sa, Lipocol s-deo, Lipocol S, Stearyl alcohol s, Crodacol s95, Octadecanol, 1-, Stearyl alcohol pc, Alfol 18 alcohol, Aec stearyl alcohol, Crodacol s-95, Kalcohl 80, Nacol 18do alcohol, Conol 30F, Nikkol stearyl alcohol, CCRIS 3960, Rofamol, Sabonal c 18 95, CO-1897, Nacol 18-94 alcohol, Nacol 18-98 alcohol, Nacol 18-99 alcohol, Conol 1675, HSDB 1082, Octadecanol NF, Crodacol S, NSC 5379, NSC-5379, 1-stearyl alcohol, EINECS 204-017-6, UNII-2KR89I4H1Y, BRN 1362907, 2KR89I4H1Y, DTXSID8026935, CHEBI:32154, Kalcohl 8098, OCTADECENOL-, AI3-01330, Adol 62, C18H38O, NSC5379, CO 1895F, MFCD00002823, Stearyl alcohol [JAN:NF], Stearyl alcohol [USAN:JAN], STEARYL ALCOHOL 98/F, STEARYL ALCOHOL 98/P, DTXCID306935, N-OCTADECYL-D37 ALCOHOL, EC 204-017-6, 4-01-00-01888 (Beilstein Handbook Reference), EINECS 272-778-1, CACHALOT S-56 STEARYL ALCOHOL, 68911-61-5, NCGC00159369-02, NCGC00159369-04, STEARYL ALCOHOL (II), STEARYL ALCOHOL [II], STEARYL ALCOHOL (MART.), STEARYL ALCOHOL [MART.], STEARYL ALCOHOL (USP-RS), STEARYL ALCOHOL [USP-RS], STEARYL ALCOHOL (EP MONOGRAPH), STEARYL ALCOHOL [EP MONOGRAPH], CAS-112-92-5, stearylalcohol, Octanodecanol, Stearal, -n octadecanol, Alcool starylique, n-octadecylalcohol, Varonic BG, 1-hidroxioctadecane, Crodacol S70, Crodacol S95NF, Stearyl alcohol NF, alcohol n-Octadecil, Lanette 18DEO, stearyl alcohol pure, Aec cetearyl alcohol, Cachalot S 43, Cachalot S-56, Crodacol S 70, Crodacol S 95, Laurex 18, Octadecan- 1- ol, Philcohol 1800, Stearyl alcohol USP, Lanette 18 DEO, Alfol 18NF, Conol 30SS, Crodacol 1618, Conol 30S, Lorol C18, 86369-69-9, Crodacol S 95 NF, Kalchol 8098, Kalcohl 8099, Alfol 1618 alcohol, Adol 64, Alcohol cetylstearylicus, Alfol 1618e alcohol, Hyfatol 18-95, Hyfatol 18-98, Kalcol 8098, Lorol C 18, Speziol C 18 Pharma, Alfol 1618cg alcohol, 1-Octadecanol, 95%, SSD AF (Salt/Mix), Nacol 18-98, VLTN 6, Ceteareth-20 (Salt/Mix), SCHEMBL23810, OCTADECANOL [WHO-DD], STEARYL ALCOHOL [MI], CHEMBL24640, Stearyl alcohol (JP17/NF), STEARYL ALCOHOL [JAN], STEARYL ALCOHOL [HSDB], STEARYL ALCOHOL [INCI], WLN: Q18, STEARYL ALCOHOL [VANDF], SCHEMBL10409854, Stearyl alcohol; octadecan-1-ol, STEARYL ALCOHOL [WHO-DD], CS-D1671, HY-Y1809, Tox21_111610, LMFA05000085, STL453659, 1-Octadecanol, technical grade, 80%, AKOS009031494, Tox21_111610_1, 1-Octadecanol, ReagentPlus(R), 99%, CO 1895, CO 1897, CO 1898, Octadecan-1-ol (Langkettige Alkohole), NCGC00159369-03, LS-97715, SY011369, 1-Octadecanol, puriss., >=99.0% (GC), FT-0761208, O0006, 1-Octadecanol, Selectophore(TM), >=99.5%, EN300-19954, 1-Octadecanol, Vetec(TM) reagent grade, 94%, D01924, A802702, L000755, Q632384, SR-01000944718, J-002873, SR-01000944718-1, Z104476204, Stearyl alcohol, European Pharmacopoeia (EP) Reference Standard, 2DEF44B7-B367-4188-89E4-531379568C74, Stearyl alcohol, United States Pharmacopeia (USP) Reference Standard, Stearyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H, Octadecan-1-ol [Wiki], 112-92-5 [RN], 1362907 [Beilstein], 1-Octadecanol [ACD/Index Name] [ACD/IUPAC Name], 1-Octadecanol [German] [ACD/Index Name] [ACD/IUPAC Name], 1-Octadécanol [French] [ACD/IUPAC Name], 204-017-6 [EINECS], 2KR89I4H1Y, MFCD00002823 [MDL number], octadecyl alcohol, RG2010000, Stearyl alcohol [JAN] [JP15] [NF] [USAN], stenol, steryl alcohol, Octadecanol NF [NF], Stearal, 1-hydroxyoctadecane, 1-Octacosanol [ACD/Index Name] [ACD/IUPAC Name] [Wiki], 1-Octadecan-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d37-ol(9CI), 1-OCTADECANOL-1,1-D2, 1-Stearyl alcohol, 2-(1-adamantyl)-2-amino-acetic acid, 2-(adamantan-1-yl)-2-aminoacetic acid, 204259-62-1 [RN], 267-008-6 [EINECS], 272-778-1 [EINECS], 557-61-9 [RN], 86369-69-9 [RN], Adol 62, Atalco S, Cachalot S-56, Cetostearyl alcohol, Conol 1675, Conol 30F, Crodacol S, Crodacol S70, Crodacol S95NF, Crodacol-S, Decyl octyl alcohol, Kalcohl 80, Kalcohl 8098, Lanette 18 DEO, Lanol S, Lorol C18, n-1-octadecanol, n-octadecanol, N-OCTADECYL ALCOHOL, Octadecanol, Octadecanol, 1-, Octadecylalkohol, Octanodecanol, Octodecyl alcohol, Philcohol 1800, Polaax, Q13 [WLN], Rita SA, Rofamol, Sipol S, Siponol S, Siponol SC, SSD AF, Stearic alcohol, Stearol, Stearyl alcohol NF, Stearyl alcohol USP, Stearylalkohol, Steraffine, UNII:2KR89I4H1Y, UNII-2DMT128M1S, UNII-2KR89I4H1Y, UNII-B1K89384RJ, Varonic BG
Stearyl alcohol is a compound produced from stearic acid, a naturally occurring fatty acid.
Stearyl alcohol consists predominantly of cetyl and Stearyl alcohols and is classified as a fatty alcohol.
Stearyl alcohol is used as an opacifying agent and foaming surfactant, as well as an aqueous and non-aqueous viscosity increasing agent.
Stearyl alcohol provides an emollient feel to the skin and can be used in water-in-oil emulsions, oil-in-water emulsions, and anhydrous formulations.
Stearyl alcohol is widely used in conditioners and other cosmetic products due to Stearyl alcohol emollient properties.
Use Stearyl alcohol 1% to 25% by weight inclusion.
Stearyl alcohol itself is not an emulsifier, but must be combined with another emulsifier.
The appearance of Stearyl alcohol can be pastel or flake.
Stearyl alcohol is waxy solid alcohol formerly obtained from whale or dolphin oil and used as a lubricant and antifoam agent and to retard evaporation of water from reservoirs.
Stearyl alcohol is now manufactured by chemical reduction of stearic acid.
Stearyl alcohol is an organic compound, usually appearing in the form of white crystalline granules, derived from fats and oils.
Stearyl alcohol is in a class known as fatty alcohols, which, unlike irritating types of alcohols, do not dry out skin.
Stearyl alcohol is typically produced through hydrogenation (process change from a liquid into a solid or semi-solid state) of stearic acid.
Stearyl alcohol is a saturated fatty acid prevalent in animal fats, but rich plant sources of stearic acid include palm fruit, cocoa butter and shea butter.
The Stearyl alcohol we use is derived from plant (non-animal) sources.
Stearyl alcohol can be used in personal care products as an emollient, helping to nourish skin and hair, leaving them soft and smooth.
Stearyl alcohol also has emulsion stabilizing properties, and can be used to help balance and add structure to oil-water formulations.
Stearyl alcohol is a long-chain primary fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of 18 carbon atoms.
Stearyl alcohol has a role as a plant metabolite, a human metabolite and an algal metabolite.
Stearyl alcohol is a long-chain primary fatty alcohol, a fatty alcohol 18:0 and a primary alcohol.
Stearyl alcohol derives from a hydride of an octadecane.
Stearyl alcohol is a natural product found in Mikania cordifolia, Stoebe vulgaris, and other organisms with data available.
Stearyl alcohol is a vegetable-derived ingredient that’s naturally found in plants, insects, and even humans.
Per our point about not all alcohols being the same, those used in skincare typically fall into one of two categories.
Stearyl alcohol is a long-chained fatty alcohol, which differs from volatile alcohols, such as denatured alcohol (also known as alcohol denat), isopropyl alcohol, and SD alcohol.
The latter are fast-drying and cooling and evaporate as soon as they’re applied onto the skin.
Stearyl alcohol is often used as astringents, preservatives, or solvents.
Stearyl alcohol is a thickener of cosmetic products, mainly creams and lotions.
A natural alcohol which is derived from Vegetable source, Stearyl alcohol changes the viscosity and adds a to creams and lotions, whilst adding stability
Stearyl alcohol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum. Stearyl alcohol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Stearyl alcohol is palm oil-derived Stearyl alcohol. Stearyl alcohol is a fatty alcohol sold in flakes, pastilles and beads available in grade and kosher preparations. Stearyl alcohol can be natural, derived from plant-based oils like palm or coconut, or they can be synthetic. Stearyl alcohol is act as emulsifiers, emollients, viscosity controllers and dispersants. Stearyl alcohol is used as chemical intermediates, most often used in surfactants to enhance foaming and cleaning properties in detergents and cleaners. Stearyl alcohol is used as a nonionic surfactant and intermediate in the manufacture of plastics, textiles and waxes. Stearyl alcohol is also used as an ingredient in various lubricants, perfumes, personal care products and more. Stearyl alcohol is manufactured from renewable palm oil sources, without the use of GMOs. Stearyl alcohol is made from a minimum 98 percent C18 and no more than 2 percent C16. Stearyl alcohol has a maximum acid value of 0.5, a maximum saponification value of 1.0 and a maximum iodine value of 2.0. Testing is performed to AOCS standards ensuring accuracy and exceptional quality control. Great care has been taken to ensure our product is safe to use in cosmetics and other applications. Stearyl alcohol is free from peanuts, tree nuts, dairy, gluten and other common allergens. Stearyl alcohol contains no residual solvents and is bovine spongiform encephalopathy/transmissible spongiform encephalopathy (BSE/TSE) free. Also, Stearyl alcohol is not tested on animals and is REACH registered. Stearyl alcohol is a fatty alcohol used as an emollient and to help keep other ingredients intact in a formulation. Stearyl alcohol is not to be confused with the drying, irritating types of alcohol such as SD alcohol or denatured alcohol. Stearyl alcohol also has cleansing and foam-boosting properties and isn’t considered drying on skin. Stearyl alcohol in its raw form is a white, waxy substance. The U.S. Food and Drug Administration has ruled Stearyl alcohol safe as a food additive, and the independent Cosmetic Ingredient Review panel deems Stearyl alcohol safe as used in cosmetics. Stearyl alcohol is a vegetable-based, highly refined fatty alcohol. Stearyl alcohol is a vegetable-based, refined fatty alcohol. Stearyl alcohol is an all-purpose, vegetable sourced, all natural and from from sustainable coconut oils. Stearyl alcohol is a very effective stabilizer, thickening agent, emulsifier, for making all kinds of lotions and creams, body butters and more. Like other fatty alcohols stearyl is an excellent natural thickener and emulsifier or co emulsifier, and imparts a nice smooth feel. Stearyl alcohol is a very useful additive in creams, lotions and more, as a secondary emulsifier, thickener, emollient, and is compatible with nearly all cosmetic ingredients. Compared to other fatty alcohols, like cetyl alcohol, in many formulations, the Stearyl alcohol will result in a slightly more softer, conditioned feel, and after-feel sensory wise, and a whiter appearance. Stearyl alcohol is a 100% natural, vegetable derived fatty alcohol, used widely in the cosmetic and personal care industry. Stearyl alcohol is commonly used to form emulsions and is used as a conditioner, emollient, emulsifier and thickener in many cosmetic and personal care products. As an emulsifier, Stearyl alcohol helps to bind and keep product ingredients from separating (oil and water), as well as giving products better spreadability. As a thickening agent and surfactant, Stearyl alcohol helps to increase the viscosity (thickness) of Stearyl alcohol and can also increase the foaming capacity. Stearyl alcohol has emollient properties and also can function as an emulsifier and thickener in products. In stick products, such as deodorants and antiperspirants, Stearyl alcohol helps to emulsify the active ingredient and fragrance into the wax base. Stearyl alcohol also helps modify the physical texture of the stick’s waxy base. Stearyl alcohol is a compound produced from stearic acid, a naturally occurring fatty acid. Stearyl alcohol is found naturally in various mammalian tissues. Stearyl alcohol is used in the biosynthesis of lipids and other naturally occurring cellular constituents and enters metabolic pathways for energy production. In the pharmaceutical and cosmetics industries Stearyl alcohol can be used as an emulsion stabilizer, fragrance ingredient, surfactant/emulsifying agent, foam booster, and as a viscosity increasing agent. Stearyl alcohol is found as an ingredient of hydrophilic ointments and petrolatums, and is also used in the preparation of creams. Stearyl alcohol appears to be poorly absorbed from the gastrointestinal tract. Stearyl alcohol is an organic compound classified as a saturated fatty alcohol with the formula CH3(CH2)16CH2OH. Stearyl alcohol takes the form of white granules or flakes, which are insoluble in water. Stearyl alcohol has a wide range of uses as an ingredient in lubricants, resins, perfumes, and cosmetics. Stearyl alcohol is used as an emollient, emulsifier, and thickener in ointments, and is widely used as a hair coating in shampoos and hair conditioners. Stearyl heptanoate, the ester of Stearyl alcohol and heptanoic acid (enanthic acid), is found in most cosmetic eyeliners. Stearyl alcohol has also found application as an evaporation suppressing monolayer when applied to the surface of water. Stearyl alcohol is prepared from stearic acid or some fats by the process of catalytic hydrogenation. Stearyl alcohol has low toxicity. Stearyl alcohol is one of the most promising fatty alcohols to be used for food applications as an oil-structuring agent. Shows peanut oil containing 2.0%, 2.5%, and 3.0% of Stearyl alcohol (C18OH). The minimum gelling concentration (MGC), that is the lowest concentration that is permitted to obtain a self-standing material, is 2.5% (w/w). As described by Valoppi et al. (2017), the MGC depends on the chain length of the fatty alcohol and decreases as the chain length of fatty alcohols increases. The MGC is also affected by the cooling rate applied: upon fast cooling, the ability of molecules to gel is reduced with a concomitant increase of the MGC. For instance, the MGC of Stearyl alcohol in peanut oil increases from 2.5% to 7.0% (w/w) upon cooling at 5 and 40°C/min, respectively. This is due to the changes in crystal size and morphology as a consequence of the cooling rate used during oleogel preparation. Stearyl alcohol is evident that a slow cooling rate (5°C/min) of oil with 5% of C18OH leads to the formation of crystal structures 10 times larger than at a fast cooling rate (40°C/min). Similar results were obtained for C16OH-, C20OH-, and C22OH-containing oleogels. Uses of Stearyl Alcohol: Stearyl alcohol is used as a substitute for cetyl alcohol in pharmaceutical dispensing. Stearyl alcohol is used in cosmetic creams and perfumery. Stearyl alcohol is used in textile oils and finishes. Stearyl alcohol is used as an antifoam agent; and in lubricants, resins, and surface active agents. Synthetic Stearyl alcohol has been approved as a direct and indirect food additive ingredient and as an ingredient in over-the-counter drugs. Substitute for cetyl alcohol in pharmaceutical dispensing, in cosmetic creams, for emulsions, textile oils and finishes. Stearyl alcohol is used as antifoam agent, lubricant, and chemical raw material. Stearyl alcohol is used in perfumery, cosmetics, intermediate, surface active agents, lubricants, resins, antifoam agent. Stearyl alcohol is used in antifoam agent. Stearyl alcohol is used in resins, and USP ointments. Synthetic Stearyl alcohol has been approved as a direct and indirect food additive ingredient and as an ingredient in over-the-counter drugs. Widespread uses by professional workers: Stearyl alcohol is used in the following products: lubricants and greases, coating products, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay, adhesives and sealants, non-metal-surface treatment products, washing & cleaning products, air care products, anti-freeze products and welding & soldering products. Stearyl alcohol is used in the following areas: building & construction work and agriculture, forestry and fishing. Stearyl alcohol is used for the manufacture of: , mineral products (e.g. plasters, cement), machinery and vehicles, rubber products and plastic products. Other release to the environment of Stearyl alcohol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Uses at industrial sites: Stearyl alcohol is used in the following products: lubricants and greases, fillers, putties, plasters, modelling clay, coating products, adhesives and sealants, non-metal-surface treatment products and pH regulators and water treatment products. Stearyl alcohol is used in the following areas: building & construction work and mining. Stearyl alcohol is used for the manufacture of: chemicals, , mineral products (e.g. plasters, cement) and machinery and vehicles. Release to the environment of Stearyl alcohol can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and as processing aid. Industry Uses: Antioxidant Cleaning agent Defoamer Emulsifier Fuel Intermediate Lubricants and lubricant additives Lubricating agent Monomers Not Known or Reasonably Ascertainable Other Other (specify) Paint additives and coating additives not described by other categories Processing aids not otherwise specified Solubility enhancer Solvent Surfactant (surface active agent) Viscosity modifiers Consumer Uses: Stearyl alcohol is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), coating products, anti-freeze products, finger paints, lubricants and greases and polishes and waxes. Other release to the environment of Stearyl alcohol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Other Consumer Uses: Cleaning agent Emulsifier Fuel Lubricating agent Not Known or Reasonably Ascertainable Other Other (specify) Paint additives and coating additives not described by other categories Pigment Solvent Surfactant (surface active agent) Industrial Processes with risk of exposure: Textiles (Printing, Dyeing, or Finishing) Applications of Stearyl Alcohol: Stearyl alcohol is most commonly used in all kinds of cosmetic products. Stearyl alcohol can also be successfully used in other industrial sectors. Stearyl alcohol is found in a number of detergents – Stearyl alcohol is responsible for foam stabilisation in products intended for cleaning hard surfaces. In the pulp and paper industry, Stearyl alcohol is a component of emulsion skimmers. Stearyl alcohol is a component of processing fluids, and in the paint and varnish industry serves as a component of open-time regulators. Benefits of Stearyl Alcohol: Benefits for Skin: On the flip side, because Stearyl alcohol is a fatty alcohol, Stearyl alcohol is not drying, non-irritating, and usually beneficial when used consistently. Stearyl alcohol acts as an emollient, leaving the skin feeling smooth and soft by forming a protective layer on the surface and helping to prevent moisture loss. Stearyl alcohol is often combined with cetyl alcohol (another fatty alcohol) to create Stearyl alcohol, which also has emollient properties. The primary reason Stearyl alcohol shows up in skincare products has more to do with formulation reasons and Stearyl alcohol ability to act as an emulsifier, ensuring that oil and water can be blended so that products ultimately feel thicker and more cosmetically pleasing. Functions of Stearyl Alcohol: Stearyl alcohol is a popular alcohol added to many cosmetic formulations. Stearyl alcohol action is based on the function of the solvent of active substances, the function of a preservative or emulsifier. Moreover, Stearyl alcohol has other important functions in cosmetic products: Bodying agent: As a substance with emulsion stabilising properties, Stearyl alcohol gives the desired form of a cosmetic product. Stearyl alcohol is responsible for the stabilisation of oil-in-water emulsions, water-in-oil emulsions and water-free formulations. Stearyl alcohol directly affects the viscosity of a product, giving Stearyl alcohol appropriate performance and application properties. Fatty alcohols, which include cetyl alcohol and Stearyl alcohol, are designed to stabilise the emulsion, i.e., prevent Stearyl alcohol from delaminating into water and oily components. Stearyl alcohol also provides and improves spreadability and can support foaming. Emollient: Stearyl alcohol is included in a range of cosmetics designed for skin and hair care. Stearyl alcohol creates a so-called occlusive layer on the surface. Stearyl alcohol prevents excessive evaporation of water, thus keeping skin and hair soft and smooth. For this reason, Stearyl alcohol is dedicated primarily for use on dry skin. As an emollient, Stearyl alcohol is indirectly also a cosmetic ingredient with a moisturising effect. Stearyl alcohol reduces the drying effect of anionic surfactants – leaves the skin moisturised and covered with a protective layer. Regreasing substance: Cleansing cosmetic products remove sebum and epidermal fatty substances from the skin surface. While Stearyl alcohol is desirable to thoroughly clean the skin, Stearyl alcohol also allows unwanted substances from the environment to penetrate into the deeper layers of the skin. For this reason, regreasing substances, such as Stearyl alcohol, are commonly added to cosmetics, creating a specific protective layer. Emulsifying: Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil). Emulsion stabilising: Promotes the emulsification process and improves the stability and shelf life of the emulsion. Foam boosting: Improves the quality of the foam produced by increasing one or more of the following properties: volume, texture and/or stability. Masking: Reduces or inhibits the odor or basic taste of the product. Opacifying: Reduces transparency or translucency of cosmetics. Refatting: Restores lipids in hair or in upper layers of the skin. Surfactant: Reduces the surface tension of cosmetics and contributes to the even distribution of Stearyl alcohol when it is used. Viscosity controlling: Increases or decreases the viscosity of cosmetics. Cosmetic products containing Stearyl alcohol: Hair shampoos, Hair conditioners, Cleansing milks and oils, Shower gels, Body lotions, Hand and foot creams, Aftershave creams, Body scrubs, Self-tanners, Anti-wrinkle creams, Hair removal preparations, Mascaras, Lip balms, Anti-acne preparations. Characteristics of Stearyl Alcohol: Stearyl alcohol is the name given by the INCI (International Nomenclature of Cosmetic Ingredients) to a compound non-ionic surfactant that is a mixture of cetyl alcohol and Stearyl alcohol. Both of these alcohols are fatty alcohols. Manufacturing Methods of Stearyl Alcohol: Stearyl alcohol is prepared commercially via Ziegler aluminum alkyl hydrolysis or the catalytic, high-pressure hydrogenation of stearyl acid, followed by filtration and distillation. Stearyl alcohol may also be derived from natural fats and oils. General Manufacturing Information of Stearyl Alcohol: Industry Processing Sectors: All Other Basic Organic Chemical Manufacturing All Other Chemical Product and Preparation Manufacturing Fabricated Metal Product Manufacturing Machinery Manufacturing Mining (except Oil and Gas) and support activities Not Known or Reasonably Ascertainable Oil and Gas Drilling, Extraction, and Support activities Other (requires additional information) Paint and Coating Manufacturing Paper Manufacturing Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing Petrochemical Manufacturing Petroleum Lubricating Oil and Grease Manufacturing Pharmaceutical and Medicine Manufacturing Plastics Material and Resin Manufacturing Soap, Cleaning Compound, and Toilet Preparation Manufacturing Textiles, apparel, and leather manufacturing Wholesale and Retail Trade Pharmacology and Biochemistry of Stearyl Alcohol: Bionecessity: Stearyl alcohol is found naturally in various mammalian tissues. Stearyl alcohol is used in the biosynthesis of lipids and other naturally occurring cellular constituents and enters metabolic pathways for energy production. Action Mechanism of Stearyl Alcohol: Ethanol, 1-propanol, 1-butanol, 1-pentanol and 1-octanol had essentially the same effects on the mitochondrial ultrastructure: a mixed population of small and enlarged mitochondria with poorly developed cristae. 1-dodecanol induced ultrastructural changes of mitochondria of two distinct types: a mixed population of small and enlarged mitochondria with poorly developed cristae in some hepatocytes and remarkably enlarged mitochondria with well-developed cristate in others; and Stearyl alcohol induced remarkably enlarged mitochondria in all hepatocytes. The reactivity of the fatty alcohols with cetrimide decreased with increasing chain length although branching on the tetradecanol and hexadecanol resulted in a higher reactivity. Adding Stearyl alcohol to 1-hexadecanol resulted in an increased reactivity rising to a maximum for mixtures containing 20-40% w/w Stearyl alcohol. Peak inhibition was recorded with saturated primary alcohols (64 microM) varying in chain length from 16 to 19 carbon atoms. The unsaturated alcohols (oleyl, linoleyl, and linolenyl) and the secondary alcohol (pentadecan-2-ol) were considerably less effective growth inhibitors. Stearic and palmitic acids were also ineffective. After incubation of stationary phase Leishmania donovani with [1-14C]octadecanol, about 70% of the precursor was taken up within 3 hr. Wax esters and acyl moieties of glycerolipids contained most of the 14C-activity from 3 to 6 hr, because octadecanol was partly oxidized to stearate. Ether moieties were only weakly labeled. After 40 hr, 1-0-alkyl and 1-0-alk-1'-enyl diacylglycerols as well as 1-0-alkyl and 1-0-alk-1'-enyl-2-acyl-sn-glycero-3-phosphoethanolamines contained nearly all of the radioactivity. Most of the label in the neutral ether lipids was located in the alkyl ether side chain, whereas, in the phosphatidylethanolamine fraction, most of the label was found in the alkenyl ether side chain. Human Metabolite Information of Stearyl Alcohol: Tissue Locations: Adipose Tissue Bladder Brain Epidermis Eye Lens Fibroblasts Intestine Kidney Liver Neuron Ovary Pancreas Placenta Platelet Prostate Skeletal Muscle Spleen Testis Thyroid Gland Cellular Locations: Extracellular Membrane Handling and Storage of Stearyl Alcohol: Safe Storage: Separated from strong oxidants and strong acids. First Aid Measures of Stearyl Alcohol: Eye First Aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. Ingestion First Aid: Rinse mouth. Fire Fighting: In case of fire in the surroundings, use appropriate extinguishing media. Fire Fighting Procedures: To fight fire use foam, carbon dioxide, dry chemical. Accidental Release Measures of Stearyl Alcohol: Spillage Disposal: Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations. Cleanup Methods: Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Disposal Methods of Stearyl Alcohol: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for Stearyl alcohol approved use or return Stearyl alcohol to the manufacturer or supplier. Ultimate disposal of the chemical must consider: Stearyl alcohol's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations. Identifiers of Stearyl Alcohol: CAS Number: 112-92-5 ChEBI: CHEBI:32154 ChEMBL: ChEMBL24640 ChemSpider: 7928 ECHA InfoCard: 100.003.652 PubChem CID: 8221 UNII: 2KR89I4H1Y CompTox Dashboard (EPA): DTXSID8026935 InChI: InChI=1S/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3 Key: GLDOVTGHNKAZLK-UHFFFAOYSA-N InChI=1/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3 Key: GLDOVTGHNKAZLK-UHFFFAOYAZ SMILES: OCCCCCCCCCCCCCCCCCC CAS number: 112-92-5 EC number: 204-017-6 Hill Formula: C₁₈H₃₈O Molar Mass: 270.49 g/mol HS Code: 2905 17 00 Properties of Stearyl Alcohol: Chemical formula: C18H38O Molar mass: 270.49 g/mol Appearance: White solid Density: 0.812 g/cm3 Melting point: 59.4 to 59.8 °C (138.9 to 139.6 °F; 332.5 to 332.9 K) Boiling point: 210 °C (410 °F; 483 K) at 15 mmHg (2.0 kPa) Solubility in water: 1.1×10−3 mg/L Boiling point: 330 - 360 °C Density: 0.805 - 0.815 g/cm3 (60 °C) Flash point: 195 °C Ignition temperature: 230 °C DIN 51794 Melting Point: 55 - 60 °C Vapor pressure: <1 hPa (20 °C) Bulk density: 300 kg/m3 Molecular Weight: 270.5 g/mol XLogP3: 8.4 Hydrogen Bond Donor Count: 1 Hydrogen Bond Acceptor Count: 1 Rotatable Bond Count: 16 Exact Mass: 270.292265831 g/mol Monoisotopic Mass: 270.292265831 g/mol Topological Polar Surface Area: 20.2Ų Heavy Atom Count: 19 Complexity: 145 Isotope Atom Count: 0 Defined Atom Stereocenter Count: 0 Undefined Atom Stereocenter Count: 0 Defined Bond Stereocenter Count: 0 Undefined Bond Stereocenter Count: 0 Covalently-Bonded Unit Count: 1 Compound Is Canonicalized: Yes Specifications of Stearyl Alcohol: Assay (GC, area%): ≥ 96.0 % (a/a) Melting range (lower value): ≥ 56 °C Melting range (upper value): ≤ 59 °C Identity (IR): passes test Acid Value (mg KOH/g): 0.1 Max Saponification Value (mg KOH/g): 0.5 Max Iodine Value (% I2absorbed): 0.3 Max Hydroxyl Value (mgKOH/g): 200-210 Hydrocarbon (%): 0.50 max Color (APHA): 10 Max Moisture Content (%): 0.2 Max Fatty Alcohol Content (%): 99 min Composition (%): ≤ C16: 2 Max C18: 98 min ≥ C20: 2 Max Product Form: Liquid Packaging: Drum; ISO; Bulk Names of Stearyl Alcohol: Regulatory process names: 1-Octadecanol Octadecan-1-ol octadecan-1-ol Stearyl alcohol IUPAC names: 1-Octadecanol 1-Octadecanol Alcohol C18 OCTADECAN-1-OL Octadecan-1-ol octadecan-1-ol Octadecan-1-ol octadecan-1-ol Octadecanol Octadecanol STEARYL ALCOHOL Stearyl alcohol stearyl alcohol Stearyl Alcohol Stearyl alcohol Preferred IUPAC name: Octadecan-1-ol Trade names: 1-Octadecanol Stearyl alcohol Octadecanol Octadecyl alcohol N-Octadecanol Alfol 18 CO-1897 ECOROL 18/98 ECOROL 18/98 F ECOROL 18/98 P ECOROL 18/99 P ECOROL 28 Fatty alcohol 1218 Ginol 1618 Ginol 18 Kalcol Leunapol-FA 18 MASCOL 1898 MASCOL 1898P MASCOL 68/30 (70% C18) MASCOL 68/50 (50% C18) Nacol 18 Nafol 1218 Nafol 1618 Rofanol 50/55 V Rofanol 60/65 V Rofanol 70/75 V Rofanol 80/85 V Stearyl Alcohol TA-1618 MASCOL 1898 Other names: 1-Octadecanol Octadecan-1-ol Other identifiers: 112-92-5 193766-48-2 8014-37-7 8032-19-7 8032-21-1 8034-90-0
